Multimodal Analgesia, Nonsteroidal Anti-inflammatory Drugs
Conditions
Keywords
Analgesic efficacy, knee arthroplasty, Opioid consumption, Pain Medicine, Narcotics, Multimodal Analgesia
Brief summary
This will be a single-center, prospective observational study. The study will compare post-operative pain scores and narcotic consumption between two groups of patients - one cohort will receive ibuprofen (Motrin) and Percocet (to be used as needed) while the other cohort will receive only Percocet. Both pain management options are considered to be standard of care. The primary objective of the study is to compare patients' reported pain and narcotic use following meniscectomy, and determine if NSAIDs can provide adequate pain relief.
Interventions
DRUGIbuprofen 600 mg
Ibuprofen 600 mg to be taken every 8 hours (TID) as needed (PRN
DRUGstandard oxycodone/acetaminophen
Sponsors
NYU Langone Health
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Must be at least 18 years of age * ASA class I-II * Patients scheduled for meniscectomy
Exclusion criteria
* Contraindication to ibuprofen or oxycodone/acetaminophen (e.g. hypersensitivity, history of GI or bleeding disorder) * Legally incompetent or mentally impaired (e.g. minors, Alzheimer's subjects, dementia, etc.) * Younger than 18 years of age or older than 65 * Any patient considered a vulnerable subject * Patients on pain medication prior to surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Visual analogue scale (VAS) score | 4 Hours | Scale consisting of a drawn line from 0 to 100 - you will be asked to mark where you believe your pain is (100 being worse pain). |
| Pain Verbal Rating Scale | 4 Hours | Verbal rating scale, consisting of 4 points (0 = no pain, 1 = mild, 2 = moderate, and 3 = severe). |
Countries
United States
Outcome results
None listed