Chronic Hip Joint Pain, Prearthritic Hip Disease
Conditions
Keywords
femoroacetabular impingement, labral tear, rehabilitation
Brief summary
Intra-articular, prearthritic hip disorders (PAHD) result in substantial dysfunction in young adults and are proposed precursors to hip osteoarthritis (OA). Effective treatment of PAHD is needed to improve function in the young adult and prevent or delay the onset of hip OA, however evidence related to treatment of PAHD is limited. This research will provide the foundation for a future clinical trial to assess the efficacy of movement pattern training, an innovative rehabilitation approach for the treatment of PAHD.
Detailed description
Significance: Intra-articular, prearthritic hip disorders (PAHD) result in substantial dysfunction in young adults and are proposed precursors to hip osteoarthritis. The number of surgical procedures to treat PAHD has grown exponentially in the past decade, despite the lack of high level evidence to guide treatment decisions. The potential exists for surgery to become standard treatment before rigorous investigation of treatment options has been completed. This trend may be partially due to a lack of evidence related to rehabilitation. Although some authors believe rehabilitation can improve function in people with PAHD, others state that rehabilitation is contra-indicated and recommend surgery as the best option. There are no published clinical trials to support or refute either opinion, therefore little is known about the comparative effectiveness of rehabilitation. Innovation: The investigators' long term goal is to develop effective treatment strategies for people with PAHD that will improve function and prevent or delay the onset of OA. Movement pattern training is an innovative rehabilitation approach designed to reduce stresses on the hip joint by optimizing the biomechanics of functional tasks through task-specific instruction. Preliminary work suggests that abnormal movement patterns may be associated with PAHD and that movement pattern training may be an effective treatment approach, however comparison to standard rehabilitation has not been completed. Purpose: This study was designed to assess the feasibility of conducting a multicenter randomized clinical trial (RCT) to determine the efficacy of movement pattern training compared to standard rehabilitation for people with PAHD. Participants enrolled at Washington University and University of Pittsburgh will be randomized into one of two treatment groups, movement pattern training or standard rehabilitation. In addition to assessing feasibility of the trial, preliminary estimates of effect sizes for treatment outcomes will be obtain in preparation for the future definitive trial. Post-treatment improvements in patient-reported function as measured by the Hip disability and Osteoarthritis Outcome Score and hip adduction motion during functional tasks, a proposed mechanistic factor associated with PAHD will be assessed. Upon completion of this study, the investigators will be positioned to implement a multicenter RCT to definitively assess the efficacy of movement pattern training. Impact: Ultimately, if movement pattern training is determined to be effective, it will provide a relatively inexpensive alternative to surgical intervention. Further, the theoretical concepts of movement pattern training could be used to possibly serve a role in injury prevention, as well as optimize post-surgical outcomes in those who do require surgery.
Interventions
OTHERRehabilitation
Comparison of two rehabilitation approaches
Sponsors
University of Pittsburgh
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Washington University School of Medicine
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
15 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* be 15-40 years old * report deep hip joint or anterior groin pain, confirmed upon physical exam * report pain \> 3/10 and present \> 3 months * demonstrate functional limitation with modified Harris Hip Score \<90.
Exclusion criteria
* previous hip surgery, fracture, pelvic/hip infection * pain due to high impact trauma * inflammatory disease, e.g. rheumatoid arthritis, gout * neurological involvement affecting balance * age \<15 or \>40 * Slipped Capital Femoral Epiphysis (SCFE) or Legg-Calve-Perthes Disease (LCP) * pain, numbness or tingling that radiates into the thigh * known pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of Participants Who Are Adherent to Treatment Attendance | Immediately after treatment (13 weeks after baseline) | Percentage of study participants who attend 90% (9/10) of the supervised treatment sessions. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Activities in Daily Living Subscale From Baseline to Post-treatment (13 Weeks) | Immediately after treatment (13 weeks after baseline) | The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Activities in Daily Living subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOS Activities in Daily Living from the post-treatment HOOS Activities in Daily Living . |
| Change in Hip Disability and Osteoarthritis Outcome Score (HOOS) Symptoms Subscale From Baseline to Post-treatment (13 Weeks) | Immediately after treatment (13 weeks after baseline) | The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOSSymptoms subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSSymptoms from the post-treatment HOOSSymptoms. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Change in Function Using the Patient Specific Functional Scale From Baseline to Post-treatment (13 Weeks) | Between Baseline and Immediately after treatment (13 weeks after baseline) | The Patient Specific Functional Scale (PSFS), a patient-reported outcome measure of patient-specific activity limitations. Patients are asked to identify 3-5 activities you are unable to do or having difficulties performing due to the pain or symptoms in your hip. Patients then rated level of difficulty from 0-10, 0 indicating they are unable to perform the activity and 10 indicating they are able to perform the activity at their preinjury level. The final score is an average of all scores provided. Change was calculated by subtracting the baseline PSFS from the post-treatment PSFS. |
| Change in Average Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to Post-treatment (13 Weeks) | Between Baseline and Immediately after treatment (13 weeks after baseline) | The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be worst pain imaginable. For average NPRS, patients are asked to rate what their pain was over the last week. Change was calculated by subtracting the baseline average NPRS from the post-treatment average NPRS. |
| Change in Worst Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to Post-treatment (13 Weeks) | Between Baseline and Immediately after treatment (13 weeks after baseline) | The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be worst pain imaginable. For worst NPRS, patients are asked to rate what was their worst (highest) level of pain was over the last week. Change was calculated by subtracting the baseline worst NPRS from the post-treatment worst NPRS. |
| Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) ADL Subscale From Baseline to 6 Months After Treatment Completion. | Between Baseline and 6 months after treatment completion | The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Activity Daily Living (ADL) subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSADL from the 6 month HOOSADL. |
| Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Symptoms Subscale From Baseline to 6 Months After Treatment Completion. | Between Baseline and 6 months after treatment completion | The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Symptoms subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSSymptom from the 6 month HOOSSymptom. |
| Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Pain Subscale From Baseline to 6 Months After Treatment Completion. | Between Baseline and 6 months after treatment completion | The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Pain subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSPain from the 6 month HOOSPain. |
| Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Sport Subscale From Baseline to 6 Months After Treatment Completion. | Between Baseline and 6 months after treatment completion | The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Sport subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSSPort from the 6 month HOOSSport. |
| Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) QOL Subscale From Baseline to 6 Months After Treatment Completion. | Between Baseline and 6 months after treatment completion | The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Quality of Life (QOL) subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSQOL from the 6 month HOOSQOL. |
| Change in Function Using the Patient Specific Functional Scale From Baseline to 6 Months After Treatment Completion. | Between Baseline and 6 months after treatment completion | The Patient Specific Functional Scale (PSFS), a patient-reported outcome measure of patient-specific activity limitations. Patients are asked to identify 3-5 activities you are unable to do or having difficulties performing due to the pain or symptoms in your hip. Patients then rated level of difficulty from 0-10, 0 indicating they are unable to perform the activity and 10 indicating they are able to perform the activity at their preinjury level. The final score is an average of all scores provided. Change was calculated by subtracting the baseline PSFS from the 6 month PSFS. |
| Change in Average Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 6 Months After Treatment Completion. | Between Baseline and 6 months after treatment completion | The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be worst pain imaginable. For average NPRS, patients are asked to rate what their pain was over the last week. Change was calculated by subtracting the baseline average NPRS from the 6 month average NPRS. |
| Change in Worst Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 6 Months After Treatment Completion. | Between Baseline and 6 months after treatment completion | The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be worst pain imaginable. For worst NPRS, patients are asked to rate what was their worst (highest) level of pain was over the last week. Change was calculated by subtracting the baseline worst NPRS from the 6 month worst NPRS. |
| Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) ADL Subscale From Baseline to 12 Months After Treatment Completion. | Between 12 months after treatment completion | The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Activity Daily Living (ADL) subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSADL from the 12 month HOOSADL. |
| Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Pain Subscale From Baseline to Post-treatment (13 Weeks) | Between Baseline and Immediately after treatment (13 weeks after baseline) | The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Pain subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOS Pain from the post-treatment HOOS Pain. |
| Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Pain Subscale From Baseline to 12 Months After Treatment Completion. | Between Baseline and 12 months after treatment completion | The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Pain subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSPain from the 12 month HOOSPain. |
| Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Sport Subscale From Baseline to 12 Months After Treatment Completion. | Between Baseline and 12 months after treatment completion | The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Sport subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSSport from the 12 month HOOSSport. |
| Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) QOL Subscale From Baseline to 12 Months After Treatment Completion. | Between Baseline and 12 months after treatment completion | The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Quality of Life (QOL) subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSQOL from the 12 month HOOSQOL. |
| Change in Function Using the Patient Specific Functional Scale From Baseline to 12 Months After Treatment Completion. | Between Baseline and 12 months after treatment completion | The Patient Specific Functional Scale (PSFS), a patient-reported outcome measure of patient-specific activity limitations. Patients are asked to identify 3-5 activities you are unable to do or having difficulties performing due to the pain or symptoms in your hip. Patients then rated level of difficulty from 0-10, 0 indicating they are unable to perform the activity and 10 indicating they are able to perform the activity at their preinjury level. The final score is an average of all scores provided. Change was calculated by subtracting the baseline PSFS from the 12 month PSFS. |
| Change in Average Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 12 Months After Treatment Completion. | between Baseline and 12 months after treatment completion | The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be worst pain imaginable. For average NPRS, patients are asked to rate what their pain was over the last week. Change was calculated by subtracting the baseline average NPRS from the 12 month average NPRS. |
| Change in Worst Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 12 Months After Treatment Completion. | Between Baseline and 12 months after treatment completion | The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be worst pain imaginable. For worst NPRS, patients are asked to rate what was their worst (highest) level of pain was over the last week. Change was calculated by subtracting the baseline worst NPRS from the 12 month worst NPRS. |
| Change in Glutueus Minimus Muscle Volume From Baseline to Post-treatment (13 Weeks) | Between Baseline and Immediately after treatment (13 weeks after baseline) | The outcome reported is the change (increase) in gluteus minimus muscle volume measured in centimeters cubed, using magnetic resonance imaging. Positive scores indicate an increase in volume. Change was calculated by subtracting the baseline muscle volume from the post-treatment muscle volume. |
| Change in Gluteus Minimus Muscle Fatty Infiltration From Baseline to Post-treatment (13 Weeks) | Between Baseline and Immediately after treatment (13 weeks after baseline) | The outcome reported is the change (decrease) in the proportion of fatty infiltration within the gluteus maximus muscle, measured by magnetic resonance imaging. A muscle fat index (MFI) was calculated to represent the proportion of fat within a muscle. To be able to analyze fat across the entire length of the muscle (from proximal to distal), muscle length was normalized so that 0% represented the most proximal slice and 100% represented the most distal slice. Mean MFI within every slice was then represented at every 1% of muscle length using spline interpolation. |
| Change in Gluteus Medius Muscle Volume From Baseline to Post-treatment (13 Weeks) | Between Baseline and Immediately after treatment (13 weeks after baseline) | The outcome reported is the change (increase) in gluteus medius muscle volume measured in centimeters cubed, using magnetic resonance imaging. Positive scores indicate an increase in volume. Change was calculated by subtracting the baseline muscle volume from the post-treatment muscle volume. |
| Change in Gluteus Maximus Muscle Volume From Baseline to Post-treatment (13 Weeks) | Between Baseline and Immediately after treatment (13 weeks after baseline) | The outcome reported is the change (increase) in gluteus maximus muscle volume measured in centimeters cubed, using magnetic resonance imaging. Positive scores indicate an increase in volume. Change was calculated by subtracting the baseline muscle volume from the post-treatment muscle volume. |
| Change in Gluteus Medius Muscle Fatty Infiltration From Baseline to Post-treatment (13 Weeks) | Between Baseline and Immediately after treatment (13 weeks after baseline) | The outcome reported is the change (decrease) in the proportion of fatty infiltration within the gluteus maximus muscle, measured by magnetic resonance imaging. A muscle fat index (MFI) was calculated to represent the proportion of fat within a muscle. To be able to analyze fat across the entire length of the muscle (from proximal to distal), muscle length was normalized so that 0% represented the most proximal slice and 100% represented the most distal slice. Mean MFI within every slice was then represented at every 1% of muscle length using spline interpolation. |
| Change in Gluteus Maximus Muscle Fatty Infiltration From Baseline to Post-treatment (13 Weeks) | Between Baseline and Immediately after treatment (13 weeks after baseline) | The outcome reported is the change (decrease) in the proportion of fatty infiltration within the gluteus maximus muscle, measured by magnetic resonance imaging. A muscle fat index (MFI) was calculated to represent the proportion of fat within a muscle. To be able to analyze fat across the entire length of the muscle (from proximal to distal), muscle length was normalized so that 0% represented the most proximal slice and 100% represented the most distal slice. Mean MFI within every slice was then represented at every 1% of muscle length using spline interpolation. |
| Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Symptom Subscale From Baseline to 12 Months After Treatment Completion. | Between Baseline and 12 months after treatment completion | The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Symptom subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSSymptom from the 12 month HOOSSymptom. |
| Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Sport Subscale From Baseline to Post-treatment (13 Weeks) | Between Baseline and Immediately after treatment (13 weeks after baseline) | The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Sport subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOS Sport from the post-treatment HOOS Sport. |
| Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Quality of Life (QOL) Subscale From Baseline to Post-treatment (13 Weeks) | Between Baseline and Immediately after treatment (13 weeks after baseline) | The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Quality of Life subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOS Quality of Life from the post-treatment HOOS Quality of Life. |
Countries
United States
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Movement Pattern Training (MPT) Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface.
Rehabilitation: Comparison of two rehabilitation approaches | 23 |
| Standard Rehabilitation Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load.
Rehabilitation: Comparison of two rehabilitation approaches | 23 |
| Total | 46 |
Baseline characteristics
| Characteristic | Movement Pattern Training (MPT) | Standard Rehabilitation | Total |
|---|---|---|---|
| Age, Categorical <=18 years | 1 Participants | 0 Participants | 1 Participants |
| Age, Categorical >=65 years | 0 Participants | 0 Participants | 0 Participants |
| Age, Categorical Between 18 and 65 years | 22 Participants | 23 Participants | 45 Participants |
| Age, Continuous | 27.6 years STANDARD_DEVIATION 5 | 30.2 years STANDARD_DEVIATION 5.2 | 28.9 years STANDARD_DEVIATION 5.2 |
| Measured BMI | 24.9 Kg/m^2 STANDARD_DEVIATION 6.1 | 25.6 Kg/m^2 STANDARD_DEVIATION 6.1 | 25.2 Kg/m^2 STANDARD_DEVIATION 6 |
| Race (NIH/OMB) American Indian or Alaska Native | 1 Participants | 0 Participants | 1 Participants |
| Race (NIH/OMB) Asian | 1 Participants | 0 Participants | 1 Participants |
| Race (NIH/OMB) Black or African American | 4 Participants | 0 Participants | 4 Participants |
| Race (NIH/OMB) More than one race | 1 Participants | 0 Participants | 1 Participants |
| Race (NIH/OMB) Native Hawaiian or Other Pacific Islander | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) Unknown or Not Reported | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) White | 15 Participants | 20 Participants | 35 Participants |
| Sex: Female, Male Female | 13 Participants | 12 Participants | 25 Participants |
| Sex: Female, Male Male | 9 Participants | 8 Participants | 17 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk |
|---|---|---|
| deaths Total, all-cause mortality | 0 / 23 | 0 / 23 |
| other Total, other adverse events | 0 / 23 | 0 / 23 |
| serious Total, serious adverse events | 0 / 23 | 0 / 23 |
Outcome results
Primary
Percentage of Participants Who Are Adherent to Treatment Attendance
Percentage of study participants who attend 90% (9/10) of the supervised treatment sessions.
Time frame: Immediately after treatment (13 weeks after baseline)
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| Movement Pattern Training (MPT) | Percentage of Participants Who Are Adherent to Treatment Attendance | 21 Participants |
| Standard Rehabilitation | Percentage of Participants Who Are Adherent to Treatment Attendance | 22 Participants |
Comparison: A priori criteria for success was that we would achieve 90% adherence to attending treatment sessions. Fisher's exact test compared patient adherence to treatment session rates by site and by group.p-value: 1Fisher Exact
Secondary
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Activities in Daily Living Subscale From Baseline to Post-treatment (13 Weeks)
The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Activities in Daily Living subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOS Activities in Daily Living from the post-treatment HOOS Activities in Daily Living .
Time frame: Immediately after treatment (13 weeks after baseline)
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Activities in Daily Living Subscale From Baseline to Post-treatment (13 Weeks) | 12.5 units on a scale | Standard Deviation 11 |
| Standard Rehabilitation | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Activities in Daily Living Subscale From Baseline to Post-treatment (13 Weeks) | 12.4 units on a scale | Standard Deviation 11.8 |
Comparison: We hypothesized MPT would demonstrate greater improvement in HOOS compared to Standard. Data collected at pretest and posttest were analyzed with ANCOVA where posttest was the dependent variable, pretest was the covariate, and treatment group was the independent variable which tests the null hypothesis that after adjusting for pretest, posttest is not significantly different across treatment groups.p-value: 0.3295% CI: [-6.51, 2.11]ANCOVA
Secondary
Change in Hip Disability and Osteoarthritis Outcome Score (HOOS) Symptoms Subscale From Baseline to Post-treatment (13 Weeks)
The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOSSymptoms subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSSymptoms from the post-treatment HOOSSymptoms.
Time frame: Immediately after treatment (13 weeks after baseline)
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Hip Disability and Osteoarthritis Outcome Score (HOOS) Symptoms Subscale From Baseline to Post-treatment (13 Weeks) | 15.0 units on a scale | Standard Deviation 13.2 |
| Standard Rehabilitation | Change in Hip Disability and Osteoarthritis Outcome Score (HOOS) Symptoms Subscale From Baseline to Post-treatment (13 Weeks) | 17.5 units on a scale | Standard Deviation 16.2 |
Comparison: We hypothesized MPT would demonstrate greater improvement in HOOS compared to Standard. Data collected at pretest and posttest were analyzed with ANCOVA where posttest was the dependent variable, pretest was the covariate, and treatment group was the independent variable which tests the null hypothesis that after adjusting for pretest, posttest is not significantly different across treatment groups.p-value: 0.1495% CI: [-13.1, 1.99]ANCOVA
Other Pre-specified
Change in Average Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 12 Months After Treatment Completion.
The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be worst pain imaginable. For average NPRS, patients are asked to rate what their pain was over the last week. Change was calculated by subtracting the baseline average NPRS from the 12 month average NPRS.
Time frame: between Baseline and 12 months after treatment completion
Population: Eight participants, four in each arm, were lost to followup.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Average Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 12 Months After Treatment Completion. | 1.4 units on a scale | Standard Deviation 1.9 |
| Standard Rehabilitation | Change in Average Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 12 Months After Treatment Completion. | 1.3 units on a scale | Standard Deviation 1.6 |
Other Pre-specified
Change in Average Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 6 Months After Treatment Completion.
The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be worst pain imaginable. For average NPRS, patients are asked to rate what their pain was over the last week. Change was calculated by subtracting the baseline average NPRS from the 6 month average NPRS.
Time frame: Between Baseline and 6 months after treatment completion
Population: Six participants, three in each arm, were lost to followup.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Average Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 6 Months After Treatment Completion. | 1.6 units on a scale | Standard Deviation 1.7 |
| Standard Rehabilitation | Change in Average Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 6 Months After Treatment Completion. | 1.6 units on a scale | Standard Deviation 2 |
Other Pre-specified
Change in Average Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to Post-treatment (13 Weeks)
The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be worst pain imaginable. For average NPRS, patients are asked to rate what their pain was over the last week. Change was calculated by subtracting the baseline average NPRS from the post-treatment average NPRS.
Time frame: Between Baseline and Immediately after treatment (13 weeks after baseline)
Population: One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Average Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to Post-treatment (13 Weeks) | -2.9 units on a scale | Standard Deviation 1.5 |
| Standard Rehabilitation | Change in Average Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to Post-treatment (13 Weeks) | -2.5 units on a scale | Standard Deviation 1.9 |
Other Pre-specified
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) ADL Subscale From Baseline to 12 Months After Treatment Completion.
The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Activity Daily Living (ADL) subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSADL from the 12 month HOOSADL.
Time frame: Between 12 months after treatment completion
Population: Eight participants, four in each arm, were lost to followup.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) ADL Subscale From Baseline to 12 Months After Treatment Completion. | 91.7 score on a scale | Standard Deviation 15.5 |
| Standard Rehabilitation | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) ADL Subscale From Baseline to 12 Months After Treatment Completion. | 92.2 score on a scale | Standard Deviation 10.5 |
Other Pre-specified
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) ADL Subscale From Baseline to 6 Months After Treatment Completion.
The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Activity Daily Living (ADL) subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSADL from the 6 month HOOSADL.
Time frame: Between Baseline and 6 months after treatment completion
Population: Six participants, three in each arm, were lost to followup.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) ADL Subscale From Baseline to 6 Months After Treatment Completion. | 90.4 score on a scale | Standard Deviation 10.3 |
| Standard Rehabilitation | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) ADL Subscale From Baseline to 6 Months After Treatment Completion. | 92.9 score on a scale | Standard Deviation 8.7 |
Other Pre-specified
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Pain Subscale From Baseline to 12 Months After Treatment Completion.
The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Pain subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSPain from the 12 month HOOSPain.
Time frame: Between Baseline and 12 months after treatment completion
Population: Eight participants, four in each arm, were lost to followup.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Pain Subscale From Baseline to 12 Months After Treatment Completion. | 1.4 units on a scale | Standard Deviation 1.9 |
| Standard Rehabilitation | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Pain Subscale From Baseline to 12 Months After Treatment Completion. | 1.3 units on a scale | Standard Deviation 1.6 |
Other Pre-specified
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Pain Subscale From Baseline to 6 Months After Treatment Completion.
The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Pain subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSPain from the 6 month HOOSPain.
Time frame: Between Baseline and 6 months after treatment completion
Population: Six participants, three in each arm, were lost to followup.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Pain Subscale From Baseline to 6 Months After Treatment Completion. | 1.6 units on a scale | Standard Deviation 1.7 |
| Standard Rehabilitation | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Pain Subscale From Baseline to 6 Months After Treatment Completion. | 1.6 units on a scale | Standard Deviation 2 |
Other Pre-specified
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Pain Subscale From Baseline to Post-treatment (13 Weeks)
The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Pain subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOS Pain from the post-treatment HOOS Pain.
Time frame: Between Baseline and Immediately after treatment (13 weeks after baseline)
Population: One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Pain Subscale From Baseline to Post-treatment (13 Weeks) | 18.1 units on a scale | Standard Deviation 12.9 |
| Standard Rehabilitation | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Pain Subscale From Baseline to Post-treatment (13 Weeks) | 19.0 units on a scale | Standard Deviation 9.6 |
Other Pre-specified
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) QOL Subscale From Baseline to 12 Months After Treatment Completion.
The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Quality of Life (QOL) subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSQOL from the 12 month HOOSQOL.
Time frame: Between Baseline and 12 months after treatment completion
Population: Eight participants, four in each arm, were lost to followup. One participant in the Standard arm did not complete the HOOS QOL subscale at 12 months.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) QOL Subscale From Baseline to 12 Months After Treatment Completion. | 76.6 score on a scale | Standard Deviation 19.3 |
| Standard Rehabilitation | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) QOL Subscale From Baseline to 12 Months After Treatment Completion. | 74.3 score on a scale | Standard Deviation 22.5 |
Other Pre-specified
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) QOL Subscale From Baseline to 6 Months After Treatment Completion.
The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Quality of Life (QOL) subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSQOL from the 6 month HOOSQOL.
Time frame: Between Baseline and 6 months after treatment completion
Population: Six participants, three in each arm, were lost to followup.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) QOL Subscale From Baseline to 6 Months After Treatment Completion. | 73.8 score on a scale | Standard Deviation 18.8 |
| Standard Rehabilitation | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) QOL Subscale From Baseline to 6 Months After Treatment Completion. | 75.0 score on a scale | Standard Deviation 15.6 |
Other Pre-specified
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Quality of Life (QOL) Subscale From Baseline to Post-treatment (13 Weeks)
The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Quality of Life subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOS Quality of Life from the post-treatment HOOS Quality of Life.
Time frame: Between Baseline and Immediately after treatment (13 weeks after baseline)
Population: One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Quality of Life (QOL) Subscale From Baseline to Post-treatment (13 Weeks) | 13.1 units on a scale | Standard Deviation 13.8 |
| Standard Rehabilitation | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Quality of Life (QOL) Subscale From Baseline to Post-treatment (13 Weeks) | 20.9 units on a scale | Standard Deviation 16.6 |
Other Pre-specified
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Sport Subscale From Baseline to 12 Months After Treatment Completion.
The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Sport subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSSport from the 12 month HOOSSport.
Time frame: Between Baseline and 12 months after treatment completion
Population: Eight participants, four in each arm, were lost to followup. One participant in the Standard arm did not complete the HOOS Sport subscale at 12 months.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Sport Subscale From Baseline to 12 Months After Treatment Completion. | 88.5 score on a scale | Standard Deviation 17 |
| Standard Rehabilitation | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Sport Subscale From Baseline to 12 Months After Treatment Completion. | 83.3 score on a scale | Standard Deviation 18.7 |
Other Pre-specified
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Sport Subscale From Baseline to 6 Months After Treatment Completion.
The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Sport subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSSPort from the 6 month HOOSSport.
Time frame: Between Baseline and 6 months after treatment completion
Population: Six participants, three in each arm, were lost to followup.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Sport Subscale From Baseline to 6 Months After Treatment Completion. | 83.1 score on a scale | Standard Deviation 15.7 |
| Standard Rehabilitation | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Sport Subscale From Baseline to 6 Months After Treatment Completion. | 84.1 score on a scale | Standard Deviation 15.2 |
Other Pre-specified
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Sport Subscale From Baseline to Post-treatment (13 Weeks)
The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Sport subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOS Sport from the post-treatment HOOS Sport.
Time frame: Between Baseline and Immediately after treatment (13 weeks after baseline)
Population: One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Sport Subscale From Baseline to Post-treatment (13 Weeks) | 24.4 units on a scale | Standard Deviation 18.1 |
| Standard Rehabilitation | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Sport Subscale From Baseline to Post-treatment (13 Weeks) | 21.6 units on a scale | Standard Deviation 15.6 |
Other Pre-specified
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Symptoms Subscale From Baseline to 6 Months After Treatment Completion.
The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Symptoms subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSSymptom from the 6 month HOOSSymptom.
Time frame: Between Baseline and 6 months after treatment completion
Population: Six participants, three in each arm, were lost to followup.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Symptoms Subscale From Baseline to 6 Months After Treatment Completion. | 79.8 score on a scale | Standard Deviation 14.5 |
| Standard Rehabilitation | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Symptoms Subscale From Baseline to 6 Months After Treatment Completion. | 84.0 score on a scale | Standard Deviation 12.3 |
Other Pre-specified
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Symptom Subscale From Baseline to 12 Months After Treatment Completion.
The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Symptom subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSSymptom from the 12 month HOOSSymptom.
Time frame: Between Baseline and 12 months after treatment completion
Population: Eight participants, four in each arm, were lost to followup.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Symptom Subscale From Baseline to 12 Months After Treatment Completion. | 79.7 score on a scale | Standard Deviation 20.1 |
| Standard Rehabilitation | Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Symptom Subscale From Baseline to 12 Months After Treatment Completion. | 84.7 score on a scale | Standard Deviation 12.1 |
Other Pre-specified
Change in Function Using the Patient Specific Functional Scale From Baseline to 12 Months After Treatment Completion.
The Patient Specific Functional Scale (PSFS), a patient-reported outcome measure of patient-specific activity limitations. Patients are asked to identify 3-5 activities you are unable to do or having difficulties performing due to the pain or symptoms in your hip. Patients then rated level of difficulty from 0-10, 0 indicating they are unable to perform the activity and 10 indicating they are able to perform the activity at their preinjury level. The final score is an average of all scores provided. Change was calculated by subtracting the baseline PSFS from the 12 month PSFS.
Time frame: Between Baseline and 12 months after treatment completion
Population: Eight participants, four in each arm, were lost to followup. One participant in the Standard arm did not complete the PSFS at 12 months.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Patient Specific Functional Scale From Baseline to 12 Months After Treatment Completion. | 8.0 units on a scale | Standard Deviation 2.5 |
| Standard Rehabilitation | Change in Function Using the Patient Specific Functional Scale From Baseline to 12 Months After Treatment Completion. | 7.0 units on a scale | Standard Deviation 2.8 |
Other Pre-specified
Change in Function Using the Patient Specific Functional Scale From Baseline to 6 Months After Treatment Completion.
The Patient Specific Functional Scale (PSFS), a patient-reported outcome measure of patient-specific activity limitations. Patients are asked to identify 3-5 activities you are unable to do or having difficulties performing due to the pain or symptoms in your hip. Patients then rated level of difficulty from 0-10, 0 indicating they are unable to perform the activity and 10 indicating they are able to perform the activity at their preinjury level. The final score is an average of all scores provided. Change was calculated by subtracting the baseline PSFS from the 6 month PSFS.
Time frame: Between Baseline and 6 months after treatment completion
Population: Six participants, three in each arm, were lost to followup.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Patient Specific Functional Scale From Baseline to 6 Months After Treatment Completion. | 7.2 units on a scale | Standard Deviation 2.3 |
| Standard Rehabilitation | Change in Function Using the Patient Specific Functional Scale From Baseline to 6 Months After Treatment Completion. | 7.1 units on a scale | Standard Deviation 2.1 |
Other Pre-specified
Change in Function Using the Patient Specific Functional Scale From Baseline to Post-treatment (13 Weeks)
The Patient Specific Functional Scale (PSFS), a patient-reported outcome measure of patient-specific activity limitations. Patients are asked to identify 3-5 activities you are unable to do or having difficulties performing due to the pain or symptoms in your hip. Patients then rated level of difficulty from 0-10, 0 indicating they are unable to perform the activity and 10 indicating they are able to perform the activity at their preinjury level. The final score is an average of all scores provided. Change was calculated by subtracting the baseline PSFS from the post-treatment PSFS.
Time frame: Between Baseline and Immediately after treatment (13 weeks after baseline)
Population: One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Function Using the Patient Specific Functional Scale From Baseline to Post-treatment (13 Weeks) | 1.7 units on a scale | Standard Deviation 1.7 |
| Standard Rehabilitation | Change in Function Using the Patient Specific Functional Scale From Baseline to Post-treatment (13 Weeks) | 1.8 units on a scale | Standard Deviation 1.8 |
Other Pre-specified
Change in Gluteus Maximus Muscle Fatty Infiltration From Baseline to Post-treatment (13 Weeks)
The outcome reported is the change (decrease) in the proportion of fatty infiltration within the gluteus maximus muscle, measured by magnetic resonance imaging. A muscle fat index (MFI) was calculated to represent the proportion of fat within a muscle. To be able to analyze fat across the entire length of the muscle (from proximal to distal), muscle length was normalized so that 0% represented the most proximal slice and 100% represented the most distal slice. Mean MFI within every slice was then represented at every 1% of muscle length using spline interpolation.
Time frame: Between Baseline and Immediately after treatment (13 weeks after baseline)
Other Pre-specified
Change in Gluteus Maximus Muscle Volume From Baseline to Post-treatment (13 Weeks)
The outcome reported is the change (increase) in gluteus maximus muscle volume measured in centimeters cubed, using magnetic resonance imaging. Positive scores indicate an increase in volume. Change was calculated by subtracting the baseline muscle volume from the post-treatment muscle volume.
Time frame: Between Baseline and Immediately after treatment (13 weeks after baseline)
Population: This study was a planned secondary analysis using imaging data that was collected at one of the testing site, Washington University Physical Therapy. Imaging data (MRI) was collected from 27 of the 30 participants enrolled at Washington University site. MRI was not available for one participant who did not tolerate the MRI, and MRI data for two participants were excluded due to poor quality scans. Funding for the imaging was provided by the Foundation for Physical Therapy Research.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Gluteus Maximus Muscle Volume From Baseline to Post-treatment (13 Weeks) | 0.3 cm^3 | Standard Deviation 32.4 |
| Standard Rehabilitation | Change in Gluteus Maximus Muscle Volume From Baseline to Post-treatment (13 Weeks) | -3.0 cm^3 | Standard Deviation 13.3 |
Other Pre-specified
Change in Gluteus Medius Muscle Fatty Infiltration From Baseline to Post-treatment (13 Weeks)
The outcome reported is the change (decrease) in the proportion of fatty infiltration within the gluteus maximus muscle, measured by magnetic resonance imaging. A muscle fat index (MFI) was calculated to represent the proportion of fat within a muscle. To be able to analyze fat across the entire length of the muscle (from proximal to distal), muscle length was normalized so that 0% represented the most proximal slice and 100% represented the most distal slice. Mean MFI within every slice was then represented at every 1% of muscle length using spline interpolation.
Time frame: Between Baseline and Immediately after treatment (13 weeks after baseline)
Other Pre-specified
Change in Gluteus Medius Muscle Volume From Baseline to Post-treatment (13 Weeks)
The outcome reported is the change (increase) in gluteus medius muscle volume measured in centimeters cubed, using magnetic resonance imaging. Positive scores indicate an increase in volume. Change was calculated by subtracting the baseline muscle volume from the post-treatment muscle volume.
Time frame: Between Baseline and Immediately after treatment (13 weeks after baseline)
Population: This study was a planned secondary analysis using imaging data that was collected at one of the testing site, Washington University Physical Therapy. Imaging data (MRI) was collected from 27 of the 30 participants enrolled at Washington University site. MRI was not available for one participant who did not tolerate the MRI, and MRI data for two participants were excluded due to poor quality scans. Funding for the imaging was provided by the Foundation for Physical Therapy Research.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Gluteus Medius Muscle Volume From Baseline to Post-treatment (13 Weeks) | 3.1 cm^3 | Standard Deviation 7.3 |
| Standard Rehabilitation | Change in Gluteus Medius Muscle Volume From Baseline to Post-treatment (13 Weeks) | 9.6 cm^3 | Standard Deviation 8.6 |
Other Pre-specified
Change in Gluteus Minimus Muscle Fatty Infiltration From Baseline to Post-treatment (13 Weeks)
The outcome reported is the change (decrease) in the proportion of fatty infiltration within the gluteus maximus muscle, measured by magnetic resonance imaging. A muscle fat index (MFI) was calculated to represent the proportion of fat within a muscle. To be able to analyze fat across the entire length of the muscle (from proximal to distal), muscle length was normalized so that 0% represented the most proximal slice and 100% represented the most distal slice. Mean MFI within every slice was then represented at every 1% of muscle length using spline interpolation.
Time frame: Between Baseline and Immediately after treatment (13 weeks after baseline)
Other Pre-specified
Change in Glutueus Minimus Muscle Volume From Baseline to Post-treatment (13 Weeks)
The outcome reported is the change (increase) in gluteus minimus muscle volume measured in centimeters cubed, using magnetic resonance imaging. Positive scores indicate an increase in volume. Change was calculated by subtracting the baseline muscle volume from the post-treatment muscle volume.
Time frame: Between Baseline and Immediately after treatment (13 weeks after baseline)
Population: This study was a planned secondary analysis using imaging data that was collected at one of the testing site, Washington University Physical Therapy. Imaging data (MRI) was collected from 27 of the 30 participants enrolled at Washington University site. MRI was not available for one participant who did not tolerate the MRI, and MRI data for two participants were excluded due to poor quality scans. Funding for the imaging was provided by the Foundation for Physical Therapy Research.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Glutueus Minimus Muscle Volume From Baseline to Post-treatment (13 Weeks) | 0.0 cm^3 | Standard Deviation 7.9 |
| Standard Rehabilitation | Change in Glutueus Minimus Muscle Volume From Baseline to Post-treatment (13 Weeks) | 1.0 cm^3 | Standard Deviation 6.3 |
Other Pre-specified
Change in Worst Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 12 Months After Treatment Completion.
The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be worst pain imaginable. For worst NPRS, patients are asked to rate what was their worst (highest) level of pain was over the last week. Change was calculated by subtracting the baseline worst NPRS from the 12 month worst NPRS.
Time frame: Between Baseline and 12 months after treatment completion
Population: Eight participants, four in each arm, were lost to followup.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Worst Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 12 Months After Treatment Completion. | 2.1 units on a scale | Standard Deviation 2.1 |
| Standard Rehabilitation | Change in Worst Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 12 Months After Treatment Completion. | 2.5 units on a scale | Standard Deviation 2.9 |
Other Pre-specified
Change in Worst Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 6 Months After Treatment Completion.
The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be worst pain imaginable. For worst NPRS, patients are asked to rate what was their worst (highest) level of pain was over the last week. Change was calculated by subtracting the baseline worst NPRS from the 6 month worst NPRS.
Time frame: Between Baseline and 6 months after treatment completion
Population: Six participants, three in each arm, were lost to followup.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Worst Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 6 Months After Treatment Completion. | 2.8 units on a scale | Standard Deviation 2 |
| Standard Rehabilitation | Change in Worst Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 6 Months After Treatment Completion. | 2.6 units on a scale | Standard Deviation 2.5 |
Other Pre-specified
Change in Worst Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to Post-treatment (13 Weeks)
The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be worst pain imaginable. For worst NPRS, patients are asked to rate what was their worst (highest) level of pain was over the last week. Change was calculated by subtracting the baseline worst NPRS from the post-treatment worst NPRS.
Time frame: Between Baseline and Immediately after treatment (13 weeks after baseline)
Population: One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Movement Pattern Training (MPT) | Change in Worst Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to Post-treatment (13 Weeks) | -3.7 units on a scale | Standard Deviation 1.8 |
| Standard Rehabilitation | Change in Worst Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to Post-treatment (13 Weeks) | -3.9 units on a scale | Standard Deviation 3 |