Cancer
Conditions
Keywords
Geriatric assessment
Brief summary
To establish the optimal strategy of fall-risk assessment to predict falls in older adults receiving cancer therapy.
Interventions
OTHERBaseline Participant Assessment
* Section 1 contains demographic questions * Section 2 contains daily activity questions with multiple choice answers, multiple physical function questions, and if the participants has fallen and how many falls have occurred in the last 6 months * Section 3 has the participant list all medication * Section 4 contains several questions about participant health (lists of illnesses and indicate if illness interferes with their activities) * Section 5 contains several questions about participant fall concerns with answers ranging from 1=Not at all to 4=Very * Section 6 contains multiple questions asking about emotional distress/depression, fatigue, pain interference, pain intensity, and numbness and tingling
OTHERBaseline Healthcare Provider Assessment
* Cognition: Orientation-Memory-Concentration Test which contains 6 questions that the provider will ask the participant. Form items 1-3, the response is either correct (score 0) or incorrect (score 1). For items 4-6, subtract one point for each error. Total score of 11 or greater indicates cognitive impairment (maximum score =28) * Trail Making Test Part B - consists of 25 circles distributed over a sheet of paper. The circles include both numbers and letters; the participants draws lines to connect the circles in an ascending pattern, but with the added task of alternating between the numbers and letter. The test is timed. * Timed Up and Go - the provider measures the time in seconds it takes for the participant to stand up from a standard arm chair, walk a distance of 3 meters, turn, walk back to the chair, and sit down again.
OTHERFollow-up Participant Assessment
* Section 1 contains multiple choice questions about daily actives and several physical function questions * Section 2 asks the participants how many medications they take on a daily basis, indicate any medication for depression, anxiety, nausea , and other stomach conditions * Section 3 contains multiple questions asking about emotional distress/depression, fatigue, pain interference, pain intensity, and numbness and tingling
OTHERFollow-up Healthcare Provider Assessment
* Trail Making Test Part B - consists of 25 circles distributed over a sheet of paper. The circles include both numbers and letters; the participants draws lines to connect the circles in an ascending pattern, but with the added task of alternating between the numbers and letter. The test is timed. * Timed Up and Go - the provider measures the time in seconds it takes for the participant to stand up from a standard arm chair, walk a distance of 3 meters, turn, walk back to the chair, and sit down again.
OTHEREnd-of-study Participant Assessment
* Section 1 contains multiple choice questions about daily actives and several physical function questions * Section 2 asks the participants how many medications they take on a daily basis, indicate any medication for depression, anxiety, nausea , and other stomach conditions * Section 3 contains multiple questions about the participant's concern about falling with answers ranging from 1=Not at all to 4=Very * Section 4 contains multiple questions asking about emotional distress/depression, fatigue, pain interference, pain intensity, and numbness and tingling
OTHEREnd-of-study Healthcare Provider Assessment
* Cognition: Orientation-Memory-Concentration Test which contains 6 questions that the provider will ask the participant. Form items 1-3, the response is either correct (score 0) or incorrect (score 1). For items 4-6, subtract one point for each error. Total score of 11 or greater indicates cognitive impairment (maximum score =28) * Trail Making Test Part B - consists of 25 circles distributed over a sheet of paper. The circles include both numbers and letters; the participants draws lines to connect the circles in an ascending pattern, but with the added task of alternating between the numbers and letter. The test is timed. * Timed Up and Go - the provider measures the time in seconds it takes for the participant to stand up from a standard arm chair, walk a distance of 3 meters, turn, walk back to the chair, and sit down again.
Sponsors
Washington University School of Medicine
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age ≥65 * Receiving systemic cancer therapy, including conventional chemotherapy, novel/targeted agents or hormonal agents (e.g. anti-estrogen or anti-androgen) OR will begin systemic therapy within the next 4 weeks. * Estimated life expectancy \>1 year * Anticipated to receive ongoing care at Siteman Cancer Center and its satellite sites * Able to understand and willing to sign an IRB-approved written informed consent document
Exclusion criteria
* Unable to read and understand English
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of falls | Up to 6 months | -The Prevention of Falls Network Europe (PROFANE) Consensus Group guidelines will be used |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Time to fall event | Up to 6 months | — |
| Overall survival | Up to 6 months | — |
| Number of falls that were considered injurious falls | Up to 6 months | — |
| Fear of falling as Measured by the Falls Efficacy Scale-International | Up to 6 months | measures the level of concern about falling during social and physical activities inside and outside the home whether or not the person actually does the activity. The level of concern is measured on a four point Likert scale (1=not at all concerned to 4=very concerned) |
Countries
United States
Outcome results
None listed