German Pediatric Hemophilia Research Database

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02912143

Acronym

GEPHARD

Enrollment

800

Registered

2016-09-23

Start date

2017-01-01

Completion date

2028-12-31

Last updated

2023-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Children, Drug Specific Antibodies, Hemophilia A, Hemophilia B

Brief summary

The German Pediatric Hemophilia Research Database will collect data on the prophylactic and therapeutic use of factor concentrates, complications, outcome measures (joint scores, QoL) and living circumstances in newly diagnosed children with hemophilia.

Interventions

OTHERdocumentation only

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 18 Years

Healthy volunteers

Inclusion criteria

* hemophilia A or B * FVIII/FIX \<1% to 25% * informed consent

Exclusion criteria

* no consent

Design outcomes

Primary

Measure	Time frame	Description
Number of patients with antibody developement to exogenous clotting factors (>0.5 BU)	5 years	Blood Test: measurement in Bethesda Units, positive according to local standards, for most labs \> 0.5 BU

Countries

Germany

Contacts

Primary ContactChristoph Königs, PhD

christoph.koenigs@kgu.de+496963018

Backup ContactChristoph Bidlingmaier, MD

Christoph.bidlingmaier@med.uni-muenchen.de+498944005

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026