Infective Endocarditis in the Elderly

Infective Endocarditis in the Elderly: Description of the Geriatric Characteristics and Their Influence on Therapeutic Care and the Morbidity and Mortality at 3 Months (ELDERL-IE)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02910856

Acronym

ELDERL-IE

Enrollment

120

Registered

2016-09-22

Start date

2015-03-31

Completion date

2017-07-31

Last updated

2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infective Endocarditis

Brief summary

ELDERL-IE is a multicenter national prospective observational study. The main objective is to describe geriatric characteristics (comorbidities, cognitive status, autonomy, nutritional status, balance and walking) in patients aged 75 years or older with infective endocarditis (IE). The secondary objectives are to assess the impact of geriatric features on the medico - surgical care and on morbidity and mortality at 3 months after the end of the hospitalization, and to describe the initial clinical presentation and diagnostic modalities in the IE elderly.

Detailed description

Population monitoring: Clinical, therapeutic, biological, microbiological, echocardiographic and geriatric data are collected. (M-2/3 before inclusion; D-15 before inclusion; D0; M3; vital status at 1 year)

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

75 Years to No maximum

Healthy volunteers

Inclusion criteria

: * all patients older than 75 years are eligible if they are considered and treated as a case of IE by physicians ensuring their medical care. * the patient should be treated in one of the clinical sites participating at the study. * the patient should benefit during initial hospitalization of a geriatric assessment, in addition to the usual clinical and therapeutic management of such patients.

Exclusion criteria

: * patients not fulfilling the criteria of definite or possible endocarditis according to Duke modified by Li diagnostic classification that will be applied after collection of all the data at the discharge of the patient.

Design outcomes

Primary

Measure	Time frame	Description
Change from baseline geriatric characteristics at 3 months	3 months after inclusion	OMS score

Secondary

Measure	Time frame	Description
Three months mortality	3 months after inclusion	Mortality rate at 3 months
One year mortality	1 year after inclusion	Mortality rate at 1 year
Change from baseline geriatric characteristics at 3 months	3 months after inclusion	Karnofsky'score

Countries

France

Outcome results