Osteoarthrosis
Conditions
Brief summary
The role of tobacco in osteoarthritis remains controversial. The Khoala cohort is the first multicenter French cohort of subjects with knee and / or hip osteoarthritis prevalent . It guarantees its methodology great representativeness and therefore an interesting material for the study of risk factors in the population. In addition, it should have little here Radiographs of hands for all its patients. It therefore has the opportunity to study a possible relationship between tobacco and hip osteoarthritis , knee and hand but also to study the relationship between tobacco and structural evolution of hip osteoarthritis and / or symptomatic knee.
Interventions
None listed
Sponsors
Centre Hospitalier Universitaire de Nice
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
40 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Men or women aged between 40 and 75 years * hip osteoarthritis and / or knee ( stifle ) , unilateral or bilateral , symptomatic with a confirmed diagnosis and meeting the ACR criteria , representative of prevalent cases in France during the constitution of the cohort * Affiliation to social security
Exclusion criteria
* Presence of a hip or knee prosthesis of the painful joint at baseline ; * Antecedent osteotomy ; * severe comorbidity likely to affect significantly the quality of life or induce a major healthcare consumption regardless of osteoarthritis ; * Knee pain with patellofemoral osteoarthritis isolated , that is to say without tibiofemoral osteoarthritis associated ; * Other pathologies of these joints * adults subject to a legal protection measure or unable to express their opposition not to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| relationship between smoking and severity of functional impairment in patients with osteoarthritis of hip and knee osteoarthritis using datas from cohort KOHALA | 5 years |
Outcome results
None listed