Medication Adherence
Conditions
Keywords
Kidney Transplantation
Brief summary
The overall goal of the Teen Adherence in KidnEy transplant Improving Tracking TO Optimize Outcomes (TAKE-IT TOO) study is to adapt the successful TAKE-IT intervention, aimed at improving medication adherence in adolescent kidney transplant, for use in 'real world' clinical care. The specific aims of Stage 1 of this study are: (1) To understand the needs and preferences of stakeholders (kidney transplant recipients, parents, and healthcare professionals (HCP)) in order to optimize the TAKE-IT intervention for 'real world' use.
Detailed description
TAKE-IT TOO is a prospective, 3-stage, sequential study using user-centered design techniques throughout. This entry describes Stage 1of TAKE-IT TOO. In Stage 1 we will conduct focus groups (FG) to gather data about the needs and preferences of stakeholders to inform adaptation of the Teen Adherence in Kidney transplant Effectiveness of Intervention Trial (TAKE-IT) intervention and features of a novel e-pillbox and adherence-tracking website. The protocols for Stages 2 and 3 will be submitted separately.
Interventions
OTHERFocus Group
Concurrently at each site, an experienced facilitator, having no direct affiliation with the clinical team, will use standardized stakeholder-specific, semi-structured scripts (designed with patient and parent collaborators) to conduct the patient, parent, and HCP focus groups. The TAKE-IT intervention will be described, and Simplemed e-pillbox shown, to all focus groups. Questions posed to the patient and parent focus groups will focus on 2 themes: the intervention and electronic monitoring. Example stakeholder-specific scripts to guide the discussions are appended. Each focus group will last \ 90 min. and be audio-recorded. An observer will take field notes.
Sponsors
University of Pittsburgh
St. Louis Children's Hospital
Seattle Children's Hospital
St. Justine's Hospital
The Hospital for Sick Children
British Columbia Children's Hospital
Temple University
Université de Montréal
Beth Foster
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
12 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Patients: Prevalent kidney-only transplant recipients 12-24 y, ≥3 months post-transplant. * Parents: Parents of prevalent kidney-only transplant recipients 12-17 y (followed in a participating transplant center). Parents will be eligible to participate even if their child does not participate. * HCP: transplant healthcare professionals (including representatives from variety of disciplines typically involved in promoting medication adherence)
Exclusion criteria
* Patients: Individuals with significant neurocognitive disabilities limiting their ability to understand and participate in their own care. Multiorgan transplant recipients. Patient or parent unable to communicate in English or French (Montreal only) * Parents: Parents of patients 18-24 years old will be excluded
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Stakeholders' needs and preferences | 90 minutes | needs and preferences of young kidney transplant recipients, their parents, and HCP regarding electronic monitoring and adherence interventions |
Countries
Canada, United States
Outcome results
None listed