Calanus Oil Supplementation and Maximal Oxygen Uptake

Effect of Copepod Oil Supplementation (Calanus Finmarchicus) on Endurance and VO2max in Healthy Obese Subjects

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02908828

Enrollment

Registered

2016-09-21

Start date

2016-10-31

Completion date

2017-09-19

Last updated

2020-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Biological Products/therapeutic use, Copepoda, Dietary Supplements, Fish Oils, Fatty Acids, Omega-3, Oxygen Consumption, Calanus, Maximal oxygen uptake, Zooplankton

Brief summary

Copepod oil is extracted from the marine copepod Calanus finmarchicus, the dominant plankton species in the marine food web in the Norwegian Sea. Copepods constitute the largest renewable and harvestable resource in the Norwegian Sea and adjacent waters, and it is now developed knowledge and technology for sustainable harvesting of this new resource. The purpose of this study is to investigate whether Calanus copepod oil supplementation has an equivalent effect on maximal oxygen uptake in humans to that seen in experimental studies in mice.

Interventions

DIETARY_SUPPLEMENTCalanus oil

DIETARY_SUPPLEMENTplacebo dietary oil

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

30 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* in good health * Body mass index (BMI) between 18,5 and 29,9

Exclusion criteria

* Medical condition limiting VO2max (COPD or asthma). * diagnosed coronary artery disease * Any other significant medical condition * medication effecting exercise capacity (e.i. betablockers) * Pregnancy * Participation in other clinical trials * Shellfish allergies * Systolic blood pressure \> 170 mmHG, or diastolic BP \> 105 mmHG. * contraindications for maximal exercise testing

Design outcomes

Primary

Measure	Time frame	Description
maximal oxygen uptake (VO2max)	6 months	Measured with indirect calorimetry at a treadmill (running/walking) with gradually increasing work load until exhaustion. After 10-15 min with warmup at 70% of maximal heart rate, work load will be increased every 1-2 minute and the changes maximal oxygen uptake (VO2) will be recorded automatically.

Secondary

Measure	Time frame	Description
Body composition (InBody, Japan)	6 months	—
Self-reported physical activity	6 months	assessed with International Physical Activity Questionnaire (IPAQ) short version

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026