Comparing of Microcoil Localization and Hook Wire Localization for Resectable Pulmonary Small Nodules

Comparing of Computed Tomography Guided Microcoil Localization and Hook Wire Localization for Pulmonary Small Nodules and Ground-glass Opacity Prior to Thoracoscopic Resection

Status

UNKNOWN

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02908646

Enrollment

Registered

2016-09-21

Start date

2016-06-30

Completion date

2017-07-31

Last updated

2016-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracic Surgery

Brief summary

Both of microcoil localization and hookwire localization have been proved as good preoperative CT(computed tomography)-guided techniques to guide VATS resection for the diagnosis of small peripheral pulmonary nodules technique to guide VATS resection for the diagnosis of small peripheral pulmonary nodules. The objective of this study is to determine if microcoil localization for pulmonary nodules can be safer than hookwire localization

Detailed description

Both of microcoil localization and hookwire localization have been proved as good preoperative CT-guided techniques to guide VATS resection for the diagnosis of small peripheral pulmonary nodules technique to guide VATS(video assisted thoracoscopic surgery) resection for the diagnosis of small peripheral pulmonary nodules. Compared with the commonly used hook wire, the platinum microcoil can be retained in the patients'body and the configuration of which had an effect in reducing the severity of complications. The fibered microcoil may promote blood coagulation of the surrounding lung tissues, block the needle pathway, and decrease the severity of pneumothorax and bleeding caused by the puncture needle, which has been proven in animal experiments. The objective of this study is to determine if microcoil localization for pulmonary nodules can be safer than hookwire localization

Interventions

PROCEDUREmicrocoil localization

CT-guided localization by placing a microcoil into the lung parenchyma

PROCEDUREhookwire localization

CT-guided localization by placing a hookwire into the lung parenchyma

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* solid nodules with a diameter ≤1 cm and distance to visceral pleura ≥0.5 cm, -ground-glass nodules, * part-solid ground-glass nodules, with a solid portion ≤1 cm and distance to the visceral pleura ≥1 cm. * peripheral nodules amenable to thoracoscopic wedge excision of the nodules.

Exclusion criteria

* Patients combined with pneumothorax. * Patients combined with pleural effusion. * Patients with history of hemoptysis. * Patients with medical condition that the radiologist and surgeon disagree for inclusion.

Design outcomes

Primary

Measure	Time frame	Description
complications after CT-guided localization	1 years	any complication occured after CT-guided localization

Secondary

Measure	Time frame	Description
major complications after CT-guided localization	1 years	major complication refers to complication that need to be interfered before surgery
success of the intervention of localization	1 year	success of the intervention of CT guided localization by microcoil or hookwire
success of the localization by thoracoscopic surgery	1 year	success of the localization by thoracoscopic surgery under the guide of the planted microcoil or hookwire

Countries

China

Contacts

Primary ContactXizhao Sui, MD

eastlifer@sina.com

Backup ContactHui Zhao, MD

zhaohui@pukph.edu.cn

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026