Infections - Bacterial, Pneumonia - Bacterial
Conditions
Brief summary
This is a prospective study of up to 250 participants, from birth to 18 months, who have already had a chest x-ray while a patient at the National Institute of Health (NICH) in Karachi, Pakistan. Participants will include both males and females as well as all races and ethnicities. Participants will have thermal pictures of their chest taken by trained study staff using a Smartphone and a FLIR ONE attachment. Thermal images will be read by trained radiologists to determine if bacterial pneumonia is present. Results of the thermal image will then be compared to the results of the chest x-ray. If additional images of the chest or other areas of suspected related infection are available, additional thermal images will be taken of the same location within 24 hours of the other image.
Interventions
DEVICEFLIR ONE
Sponsors
United States Agency for International Development (USAID)
Massachusetts General Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
No minimum to 18 Months
Healthy volunteers
No
Inclusion criteria
* 18 months or younger; * patient at NICH Hospital in Karachi, Pakistan; * had chest x-ray within last 24 hours to determine diagnosis of bacterial pneumonia; * consent obtained from one parent
Exclusion criteria
* thermal image cannot be done within 24 hours of chest x-ray
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| diagnosis of bacterial pneumonia | 24 hours | Pneumonia is defined as the presence of an airspace opacity, lobar consolidation, or interstitial opacities on a chest x-ray. This determination will be made by two independent radiologists blinded to each other's readings, clinical information and thermal images. If they agree that pneumonia is either present or absent, that will be the final diagnosis. If there is disagreement, a third independent, blinded radiologist will break the tie. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| diagnosis of additional site of infection possibly related to bacterial pneumonia | up to a maximum of 28 days after original chest x-ray to diagnose pneumonia is taken | Thermal imaging will be used to image other potential sites of infection suspected of being related to the bacterial pneumonia if suspected by physician |
Countries
Pakistan
Outcome results
None listed