Pediatrics
Conditions
Brief summary
We aim to increase our knowledge of the impact of preterm birth on the maturation of the visual and auditory systems and on the development of multisensory perception Specifically, we aim to evaluate the preterm infants' capabilities of detection and discrimination of different visual and auditory stimuli according to gestational age, post menstrual age and the duration of the postnatal life. A secondary aim is to compare this competencies in preterm and full term control art term equivalent age. The final aim is to optimize the hospital environment in order to make it correspond to the expectations and sensory abilities of very preterm infants. Our hypothesis is that preterm birth exposes the infants to numerous atypical stimuli which could accelerate the processes of sensory maturation
Interventions
BEHAVIORALcollection data
BEHAVIORALIRM
Sponsors
University Hospital, Strasbourg, France
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
23 Weeks to 42 Weeks
Healthy volunteers
No
Inclusion criteria
* Newborn less than 32 weeks PMA hospitalized in the Hospital of Hautepierre, Strasbourg, France) * Consent obtained from both parents * Social insurance coverage
Exclusion criteria
* Any known malformation * Brain lesions discovered on brain ultrasound (Intra-Ventricular hemorrhage grade III or IV periventricular Leukomalacia). * Unstable clinical State * Retinopathy Of Prematurity stage\> 2 or in zone 1 * Family history of abnormal color vision. * Abnormalities in auditory testing * Transfer to another hospital expected before 40 week PMA
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| visual stimulus detection with luminance | 3 months | in green condition in hospital, luminance ( 100 and 300 lux ) and color (blue- red-yellow- white) variables |
| auditory stimulus detection with parents voice | 3 months | use parents voice, pure sound of 500 Hz |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| behavioral responsiveness to visual stimuli calibrated collected from video recordings | 3 months | Evaluate the facial expression of the imitation abilities in preterm and term neonates at term. The interpretation of the behavioral responses of newborns to mimic presented by the experimenter will be working independently by two observers with a coding grid |
Countries
France
Contacts
Primary ContactClaire KOENIG ZORES, MD
Backup ContactPierre KUHN, MD
Outcome results
None listed