Children, Malnutrition, Treatment
Conditions
Brief summary
In order to make Cambodia independent from importing a product for the treatment and prevention of malnutrition, UNICEF, DFPTQ Fisheries Administration and IRD have started a collaboration for the development of a range of products for the treatment and prevention of malnutrition. To reduce costs of the product, and to adapt the taste to local circumstances, the protein source of the usual RUTF (milk powder) has been changed to fish (Trey Riel). The main objective of this sub-study is to test the efficacy of the newly developed RUTF on the recovery of children suffering from severe acute malnutrition. As comparison, the current treatment of SAM with BP-100 will be used.
Interventions
DIETARY_SUPPLEMENT2 months of treatment
standard 2 months of treatment
Sponsors
Ministry of Agriculture, Forestry and Fisheries Cambodia
UNICEF
Institut de Recherche pour le Developpement
Study design
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
6 Months to 5 Years
Healthy volunteers
No
Inclusion criteria
* discharged from hospital after admission for SAM * WHZ \<2.8 Z-score or MUAC\<11.5 cm * no complications * passing the appetite test
Exclusion criteria
* \<6 mo of age * complications related to SAM
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| weight gain | 2 months | weight gain in g/kg/day |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| body composition | 2 months | changes in body composition obtained from skinfold thickness measurements over the treatment period |
| Fatty Acid composition | 2 months | changes in serum concentrations of fatty acids over the intervention period |
Countries
Cambodia
Outcome results
None listed