Impaired Glucose Tolerance
Conditions
Keywords
pulses, beans, blood glucose, insulin
Brief summary
The objective of this study is to compare the glycemic and insulinemic response elicited by ½ cup servings of 6 beans to those elicited by ½ cup servings of mashed potato, macaroni, rice and corn.
Detailed description
In order for a food to be able to claim a reduced glycemic response, it must be shown that a typical serving of the food elicits a significantly lower blood glucose responses compared to a serving of an appropriate control food. While many studies have examined the GI of beans, few studies have compared the glycemic impact of a typical serving of beans to a typical serving of other starchy foods. Therefore, there are insufficient data to allow for a claim that beans have a low glycemic response. In addition, in order to make a claim of a reduced glycemic response, regulatory agencies also require that the insulinemic response to a food is not disproportionately increased.
Interventions
OTHERBean Type
1/2 cup of freshly boiled beans will be eaten by participants on separate study visits
OTHERStarchy Foods
1/2 cup serving of one of 4 starchy foods will be eaten by participants on different study visit
Sponsors
Glycemic Index Laboratories, Inc
Ontario Bean Growers Association
Guelph Food Research Centre
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* Male or non-pregnant females, 18-75 years of age, inclusive * Body mass index (BMI) \< 40 kg/m² * Willing to maintain habitual diet, physical activity pattern, and body weight throughout the trial and to refrain from smoking for 12hr prior to each visit. * Normal fasting serum glucose (\<7.0mmol/L capillary corresponding to whole blood glucose \<6.3mmol/L). * Understanding the study procedures and willing to provide informed consent to participate in the study and authorization to release relevant protected health information to the study investigator.
Exclusion criteria
* Failure to meet any one of the inclusion criteria * Known history of AIDS, hepatitis, diabetes or a heart condition * Subjects using medications or with any condition which might, in the opinion of Dr. Wolever, the Medical Director of GI Labs, either: 1) make participation dangerous to the subject or to others, or 2) affect the results. * Major trauma or surgical event within 3 months of screening. * Unwillingness or inability to comply with the experimental procedures and to follow GI Labs safety guidelines. * Known intolerance, sensitivity or allergy to any ingredients in the study products.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Glycemic Response | 120 minutes | post prandial blood glucose response |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Insulin Response | 120 minutes | post prandial blood insulin response |
Countries
Canada
Outcome results
None listed