Parathyroid Auto-transplantation: Prospective Randomized Trial of the Personalized Site

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02906748

Enrollment

280

Registered

2016-09-20

Start date

2016-04-30

Completion date

2018-09-30

Last updated

2016-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parathyroid Autologous Transplantation

Keywords

parathyroid autografting, thyroidectomy, survival rate, hypoparathyroidism

Brief summary

The functional parathyroid auto-transplantation (PA) could release parathyroid hormone (PTH) into the circulatory system of the body through the capillaries. But when parathyroid glands were auto-grafted in the sternocleidomastoid muscle, it would be inconvenient to detect PTH to examine whether the graft functions. So the investigators took the forearm as the aim place for auto-transplantation, either subcutaneous or brachioradialis, with its relatively fixed - antecubital vein blood test which is simple. The survival criteria is assumed as the PTH gradient of 1.5 times or greater through comparing the bilateral PTH value in grafted and not-grafted forearm.

Interventions

PROCEDUREinjection with a syringe in new-site for parathyroid autografting

new-site for parathyroid autografting, close to the antecubital vein

PROCEDUREinjection with a syringe in traditional site for parathyroid autografting

traditional-site for parathyroid autografting,not intensively close to the antecubital vein

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

10 Years to 80 Years

Healthy volunteers

Inclusion criteria

* patients with indications for PA treatment during cervical surgery

Exclusion criteria

* patients suffering secondary hypoparathyroidism with forearm fistulization

Design outcomes

Primary

Measure	Time frame	Description
parahthyroid hormone gradient by comparing between grafted and non-grafted forearm	1 months, 3 months and 6 months	The survival criteria is that the gradient of parathyroid hormone reaches 1.5 time or greater by comparing between grafted and non-grafted forearm

Secondary

Measure	Time frame
hypoparathyroidism: parathyroid hormone less than 15pg/ml(range from 15 to 65pg/ml)	6 months

Countries

China

Contacts

Primary ContactGaosong Wu, PhD

wugaosongtj@163.com0086-138-7144-4606

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 4, 2026