Machado-Joseph Disease
Conditions
Keywords
SCA 3, Ataxic Gait
Brief summary
Few studies evaluated the efficacy of adding weights on the lower limbs in patients with ataxic disorders. There is no current evidence on which would be the most appropriate weight for use in this context. To assess progress and benefits of using this load, gait of symptomatic carriers of spinocerebellar ataxia type 3/Machado Joseph disease the objective of the study is to evaluate the gait with and without different load weights on lower limbs. Outcomes were the Scale for the Assessment and Ataxia Rating of (SARA), kinematic gait assessment by the accelerometer and gyroscope and the Patient Global Impression (PGI) about which weight they prefer for walking.
Interventions
DEVICEWeight in Lower Limbs
Sponsors
Federal University of Health Science of Porto Alegre
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patients should have between 18 and 65 years of age and independent gait
Exclusion criteria
* Were the need of assistive devices for walking ≤ 10m (such as crutches, wheelchairs and orthotics) * Item gait of Scale for the Assessment and Rating of Ataxia (SARA)19≥, presence of other neurological disease that affect motor system * Orthopedic impairments of lower limbs (fractures or surgeries in the past 6 months) * Difference between the lower limbs greater than 3.0 cm
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gait speed analysis [speed (mt/min) of walking for 10 meters away] | speed (mt/min) of walking for 10 meters away in 1min timeout |
Secondary
| Measure | Time frame |
|---|---|
| Gait cadence analysis [cadence (steps/min) of walking for 10 meters away] | cadence (steps/min) of walking for 10 meters away in 1min timeout |
Outcome results
None listed