Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Post-operative Pain After Direct Anterior Total Hip Arthroplasty

Prospective Randomized Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Post-operative Pain After Direct Anterior Total Hip Replacement

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02904993

Acronym

DA THA pain

Enrollment

Registered

2016-09-19

Start date

2016-05-31

Completion date

2016-10-31

Last updated

2016-11-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Degenerative Joint Disease

Brief summary

To compare two methods of post-operative pain management in patients undergoing total hip arthroplasty. There is a perception that the periarticular injections may not be as effective in controlling post-operative pain. Both methods are current standard of care. The investigators want to compare the outcomes of each when patients are randomized to one of the methods compared to the other method of post-operative pain control.

Interventions

OTHERL2 paravertebral block

nerve block group will receive preoperatively a L2 paravertebral block with indwelling catheter

OTHERperiarticular injection group

periarticular injection group will receive the injection cocktail towards the end of the total hip replacement prior to skin closure.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* Subject scheduled for Direct Anterior unilateral total hip replacement * Weight ≥ 50 and ≤125 kg * Intact neurological exam * Cognitively intact with ability to sign consent

Exclusion criteria

* Renal insufficiency with creatinine \> 1.5 mg/dl * Allergic to any of the following : Ropivacaine, Epinephrine, Ketorolac, Morphine sulfate, NSAIDs, Tylenol, Neurontin, Morphine, Oxycodone or Dilaudid. * Subject taking regular narcotic medications prior to surgery (20mg/day Morphine equivalents for \>7days) * Subject with prior open hip surgery who received regional anesthesia or periarticular injection for post op pain management. * Subject with contraindication for spinal anesthesia

Design outcomes

Primary

Measure	Time frame	Description
Changes in pain score	post-operative to 7 days	Static and dynamic post-operative pain scores, measured on a 1 - 10 visual analogue scale.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026