Measles
Conditions
Keywords
SMS reminder, incentive, mobile phone, Immunization
Brief summary
The overall objective is to test the impact of short message service (SMS) reminders, with or without unconditionally provided mobile-money incentives, can improve measles vaccination coverage in rural western Kenyan infants.
Detailed description
Primary Objective The primary objective is to determine if text message reminders, with or without unconditionally provided incentives, can increase the proportion of children who receive measles vaccination by 15% at age ten months as compared to control arm children. Secondary Objectives 1. To conduct a secondary analysis of the primary outcome using survival analysis and time-to-immunization curves. 2. To determine if there is a differential effect on measles vaccine coverage based on mobile phone ownership and distance to the clinic. 3. To examine the effect of the interventions on measles coverage measured at twelve months of age. 4. To examine the completeness and costs of identifying children through a CHW approach versus the standard HDSS approach. 5. To evaluate the effect of the interventions on coverage of second dose of measles vaccine at 24 months. This secondary objective is contingent on receiving additional funding.
Interventions
BEHAVIORALSMS reminder
Caregivers will receive two text message reminders for their child's measles immunization scheduled for 9 months of age
BEHAVIORALUnconditional Incentive
A mobile-money incentive in the amount of 150 Kenyan Shillings will be transferred to the enrolled caregiver's mobile phone when the child reaches nine months of age
Sponsors
Kenya Medical Research Institute
Bill and Melinda Gates Foundation
Johns Hopkins Bloomberg School of Public Health
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Caregiver of infant aged 6-8 months at time of enrollment * Self-reported resident of one of the study villages; where the definition of a resident is defined by caregiver * Willing to sign informed consent for the study
Exclusion criteria
* Child of enrolled caregiver has already received one dose of measles vaccine, not including any supplemental measles vaccines * Caregiver plans to move away in the next 6 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Measles vaccination coverage | 10 months | Proportion of children receiving measles vaccination by 10 months of age by study arm |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Time to measles vaccination (in days) using Kaplan-Meier Survival Analysis | 12 months | As a secondary analysis of the primary outcome, time-to-measles immunization curves will be constructed using the Kaplan-Meier method and study arms will be compared using the Cox model. The 25th, 50th, and 75th percentiles for time to immunization and the number of days delayed, in relation to the measles due date, will also be reported for each vaccine and by study arm. |
| Proportion of children who receive measles vaccination stratified by demographic variables | 10 months | A priori we will conduct sub group analyses of the primary outcome for mobile phone ownership, birth order of the enrolled caregiver's child, and time to clinic. Additional variables for subgroup analyses will come from a risk factor analysis of not receiving measles vaccination in the control arm |
| Measles vaccination coverage at 12 months | 12 months | Proportion of children who receive measles vaccination by twelve months of age by study arm |
| Vaccination coverage for second dose of measles vaccine at 24 months. | 24 months | This outcome is dependent on receiving more funding |
Outcome results
None listed