Analgesia, Obstructive Sleep Apnea, Postpartum, Pregnancy, Respiratory Depression
Conditions
Keywords
respiratory depression, postpartum, neuraxial morphine, cesarean delivery
Brief summary
The purpose of this study is to evaluate the breathing patterns of women who undergo cesarean delivery with spinal or epidural morphine for post-operative pain control in the first day after surgery. Some women who undergo cesarean delivery may be at risk for respiratory complications related to opiate administration for post-operative pain. The primary aim of this study is to evaluate post-operative minute ventilation in women who undergo cesarean delivery using a novel method of non-invasive minute ventilation monitoring, and to see if there are predictive risk factors that may predispose women to post-operative hypoventilation.
Interventions
None listed
Sponsors
Respiratory Motion, Inc.
Duke University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* 18 years or older * planned cesarean delivery with neuraxial morphine for post-operative analgesia
Exclusion criteria
* Non-English speaking subjects * patients who undergo urgent or emergent cesarean deliveries * patients who receive general anesthesia or do not receive neuraxial morphine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in minute ventilation | baseline and 24 hours post cesarian delivery |
Secondary
| Measure | Time frame |
|---|---|
| Berlin Questionnaire | Baseline |
| STOP-BANG Questionnaire | Baseline |
| Epworth Sleepiness Scale | Baseline |
Countries
United States
Outcome results
None listed