Forced Oscillations for Diagnosis Help in Bronchiolitis Obliterans Syndrome in Post Bone Marrow Transplantation

Functional Evaluation of Distal Airways by Forced Oscillations: Diagnosis Help in Bronchiolitis Obliterans Syndrome in Post Bone Marrow Transplantation

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02902471

Acronym

OSCILLOMOELL

Enrollment

110

Registered

2016-09-15

Start date

2011-06-30

Completion date

2015-09-30

Last updated

2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone Marrow Transplantation, Bronchiolitis Obliterans

Brief summary

A study to evaluate the role of forced oscillations in diagnosis of bronchiolitis obliterans syndrome in patients after bone marrow transplantation. The force oscillations technique will be compared with classical spirometry.

Interventions

OTHERForced oscillations measure

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients over 18 years * Bone marrow or hematopoietic stem cells transplantation for more than 100 days * Clinical stability * Patients affiliated to a social security system * Patients having given his (her) written consent.

Exclusion criteria

* Bronchiolitis Obliterans already diagnosed * Unresolved Respiratory infection * Unresolved mechanical complication (pneumothorax, effusions) * Medicinal pneumopathy * Inability to perform pulmonary function tests

Design outcomes

Primary

Measure	Time frame	Description
Number of days	2 years	Temporal difference between the date of the functional change measured by the technique of the forced oscillations and by the standard techniques of plethysmography.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026