Surgical Site Infection
Conditions
Brief summary
A randomized controlled trial measuring surgical site infection rate as a function of timing of wound dressing removal.
Detailed description
A randomized controlled trial with a sample size of 602 patients to study the effect of timing of wound dressing removal on the surgical site infection rate. 300 patients were randomized to a group that had the wound dressing removed between 12-30 hours postoperatively. 302 patients were randomized to a group that had the wound dressing removal between 30-48 hours postoperatively. Statistical analyses were performed to determine if the timing of dressing removal had statistical significance on the surgical site infection rate, the primary outcome.
Interventions
OTHERWound dressing removal.
Sponsors
Albany Medical College
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Caregiver)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* patients ages 18-50 years; * medically competent (no proxies or prisoners); and * multifetal and singleton gestations from 23 0/7 weeks to 42 0/7 weeks gestational age.
Exclusion criteria
* Inability to obtain informed consent; * fetal death; * immunocompromised patients; patients taking immuno-suppressants; history of documented surgical site infection; or patients requiring reoperation within the 6 week postoperative period for indications other than wound dehiscence/debridement/infection.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Surgical Site infection Rate | 6 weeks postoperatively | Cellulitis, purulent drainage, abscess or wound requiring drainage, debridement, and antibiotics associated with a clinical diagnosis of infection. Any disruption of fascia or subcutaneous skin. |
Countries
United States
Outcome results
None listed