Comparison Between 2 Doses of Misoprostol Before Intrauterine Device

Comparison Between 2 Different Doses of Vaginal Misoprostol Before Intrauterine Device Insertion in Parous Women

Status

Completed

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02901561

Enrollment

212

Registered

2016-09-15

Start date

2016-09-30

Completion date

2017-01-31

Last updated

2017-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain Relief

Brief summary

The purpose of the investigators' study was to evaluate whether misoprostol will improve pain scores .

Detailed description

an intrauterine device can cause pain and discomfort in several ways: Use of the tenaculum to grasp the cervix and straighten the uterus for proper insertion; trans-cervical actions including measuring uterine depth, inserting the intrauterine device insertion tube, and removing the tube; and placement of the device in the uterus.

Interventions

DRUGmisoprostol 200

DRUGmisoprostol 400

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 49 Years

Healthy volunteers

Inclusion criteria

* • Women not taken analgesics or anxiolytics in the 24 hours prior insertion * Women who will accept to participate in the study

Exclusion criteria

* Any contraindication to IUD placement

Design outcomes

Primary

Measure	Time frame
Mean pain score during intrauterine device insertion	5 minutes

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026