Esophageal Manometry in Mechanically Ventilated Patients

Conditions

Acute Respiratory Failure

Keywords

esophageal pressure, chest wall elastance, lung elastance, transpulmonary pressure

Brief summary

Esophageal pressure measurements are used in to determine chest wall elastance and calculate lung elastance and transpulmonary pressure in mechanically ventilated patients. A dedicated esophageal balloon catheter is then placed in the esophagus to measure tidal variations in esophageal pressure. In this study high resolution solid-state manometry technique was used to provide detailed and continuous measurements of esophageal pressures in the different parts of the esophagus. Measurements were performed during ongoing mechanical ventilation at different levels of endexpiratory pressure.

Detailed description

Esophageal pressure measurements are used in to determine chest wall elastance and calculate lung elastance and transpulmonary pressure in mechanically ventilated patients. A dedicated esophageal balloon catheter is then placed in the esophagus to measure tidal variations in esophageal pressure. In this study high resolution solid-state manometry technique was instead used to provide detailed and continuous measurements of esophageal pressures in the different parts of the esophagus. The manometry catheter has 36 circumferential sensors at 1 cm intervals. Each sensor has 12 pressure-sensitive segments that add to the signal at that location. Measurements were performed during ongoing mechanical ventilation at different levels of endexpiratory pressure. Possible differences in tidal variations in esophageal pressure in different parts of the esophagus were assessed.

Persson P, Ahlstrand R, Gudmundsson M, de Leon A, Lundin S.

2019-06-1311 citations

10.1186/s13054-019-2484-8

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

No

Inclusion criteria

* Patients in the critical care unit receiving mechanical ventilation or Patients anesthetized and undergoing surgery

Exclusion criteria

* Patients with a contraindication to insert a catheter in the esophagus for instance due to an operation.

Design outcomes

Primary

Measure	Time frame	Description
Esophageal pressure measurements in mechanically ventilated patients	Within one hour	Esophageal pressure was measured in mechanically ventilated patients in the critical care unit and in the operating room.

Countries

Sweden

Outcome results