Mindfulness-based Stress Reduction (MBSR) Program Combined With Endurance Exercise Training: a Help in Treatment for Breast Cancer

Effect of a Mindfulness-based Stress Reduction (MBSR) Program Combined With Endurance Exercise Training: a Help to Improve Exercise Capacity and Quality of Life in Breast Cancer

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02900326

Acronym

MBSR

Enrollment

100

Registered

2016-09-14

Start date

2015-05-12

Completion date

2021-03-30

Last updated

2025-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer

Keywords

Exercise capacity, Mindfulness, Quality of life

Brief summary

Integrative approaches to promote wellness and reduce the distress associated with cancer are considered as essential components of cancer care. In case, exercise training has been shown to produce many positive physiological and psychological benefits. Mindfulness-based stress reduction program shows similar beneficial effects, and especially in emotional distress management. The aim of the study is to examine the cumulative effect of an 8 week-exercise-training program combined with an MBSR program on cardio-respiratory fitness and quality of life in women with breast cancer. These effects are thought to be mediated in part through changes in underlying brain processes, that investigators will be put in light. Through telomerase activity, oxidative stress, mitochondrial respiration and blood cytokine level measurements, investigators could expect to better understand the effect of these combined training in breast cancer.

Interventions

OTHEREndurance exercise training

In each group, there will be a comparison of aerobic capacity, quality of life (with questionnaires), functional cerebral measurements (fRMI), and telomerase activity between before and after the 8 weeks program

OTHERMindfulness-based-stress-reduction

OTHERBoth interventions together

OTHERVo2max measurements

GENETICTelomerase activity on a blood sample

OTHERQuality of life (questionnaires)

OTHERCerebral IRMf

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Breast cancer * Having completed the chemotherapy period * Undergoing radiotherapy and/or hormono therapy

Exclusion criteria

* Regular physical activity higher than 4 hours per week. * Any disease cardiac, respiratory, neurological or articular disease, which counteract the muscular training )

Design outcomes

Primary

Measure	Time frame	Description
Evolution of V02 max between inclusion and 8 weeks	8 weeks	effect of physical training associated with mental work on physical abilities of patients

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026