Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02898480

Enrollment

Registered

2016-09-13

Start date

2016-09-30

Completion date

2017-05-31

Last updated

2019-04-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Retinal Artery Occlusion, Retinal Vein Occlusion

Brief summary

Remote ischemic conditioning (RIC) is a therapeutic strategy for protecting organs or tissue against the detrimental effects of acute ischemia-reperfusion injury. It remains unknown whether this can be used in retinal vascular occlusive diseases. The purpose of the present study is to examine whether the autoregulation of retinal vessel diameters in normal persons change after remote ischemic conditioning.

Interventions

PROCEDURERemote ischemic conditioning

Briefly reversible restricting of blood flow to upper limb in four cycles of 5 minutes of inflation at 200mm Hg followed by 5 minutes of deflation.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* Normal persons

Exclusion criteria

* Present or previous eye disease * Use of medications except anti-conceptive * Epilepsy * Pregnancy or lactation

Design outcomes

Primary

Measure	Time frame
Diameter change of retinal vessel	immediate

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026