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Mindfulness for Burnout Prevention in Primary Care Providers

Evaluation of Mindfulness-based Self-care Programs for the Prevention of Burnout Among Primary Care Providers: Psychological, Inflammatory and Epigenetic Effects

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02897284
Acronym
Mind-Care
Enrollment
400
Registered
2016-09-13
Start date
2015-05-31
Completion date
2015-12-31
Last updated
2016-09-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burnout, Professional

Keywords

Mindfulness-based, Self-care, Health workers, Epigenetics

Brief summary

Burnout Syndrome is one of the major challenges for health systems worldwide. This study strives to evaluate the feasibility and effectiveness of an 8- versus 2-week mindfulness-based self-care program on burnout symptoms and psychological and biological variables.

Detailed description

The development of stepped-care interventions allows for the development of new strategies within mindfulness-based approaches, classically described as a weekly two-hour commitment which lasts eight weeks. Such approaches might reach larger and stratified groups, more suitable for usage in Brazilian health-system context. For such evaluations, the investigators will use a 3-arms randomized clinical trial design, with Sociodemographic and Labor variables, such as age, sex, number of offspring, adherence to the program, adherence to the mindfulness practices, Burnout Clinical Subtype Questionnaire -(BCSQ-36), Maslach Burnout Inventory (MBI-GS), Mindfulness Attention Awareness Scale (MAAS), Freiburg Mindfulness Inventory adapted for Brazil (FMI-Br-13), Five-Facet Mindfulness Questionnaire (FFMQ-Br). DNA methylation will be measured by Methylase-reaction, and BDNF (brain-derived neurotrophic factor) will be quantified by ELISA-sandwich. The primary outcome will be the effectiveness of such programs on different clinical subtypes of Burnout symptoms (frenetic, under challenged and worn-out). The secondary outcome will be mindfulness levels, and adherence to the program and to the mindfulness practice, and on inflammation and epigenetic variables.

Interventions

BEHAVIORALMindfulness 8 weeks

8 sessions of mindfulness

BEHAVIORALMindfulness 2 weeks

2 sessions of mindfulness

Sponsors

Centro Mente Aberta de Mindfulness
Lead SponsorOTHER
Conselho Nacional de Desenvolvimento Científico e Tecnológico
CollaboratorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes

Inclusion criteria

* Active Primary Care Providers

Exclusion criteria

* Acute disease (physical or mental) * Schizophrenia or other psychotic symptoms * Concomitant use of medication causing attentional, cognitive or concentration impairments * Having practiced mindfulness or other contemplative techniques in the previous 12 months of the study.

Design outcomes

Primary

MeasureTime frameDescription
A mindfulness intervention decreases Burnoutup to 2 months of follow-upEvaluation of Burnout symptoms through the MBI-GS scale
A mindfulness intervention increases Happinessup to 2 months of follow-upEvaluation of Happiness levels through the PHI (Pemberton) scale

Secondary

MeasureTime frameDescription
A mindfulness intervention improves Epigenetic (II)up to 2 months of follow-upEvaluation of epigenetic-related activity through Cysteine levels (Pfeiffer, 1999)
A mindfulness intervention increases Mindfulnessup to 2 months of follow-upEvaluation of Mindfulness levels through the MAAS scale
A mindfulness intervention improves Inflammationup to 2 months of follow-upEvaluation of inflammation-related activity through seric Brain-Derived Neurotrophic Factor - BDNF- (ELISA-Sandwich)
A mindfulness intervention improves Epigenetic (III)up to 2 months of follow-upEvaluation of epigenetic-related activity through Methylase Reaction (Radiomarking of methyl groups)
A mindfulness intervention improves Epigeneticup to 2 months of follow-upEvaluation of epigenetic-related activity through Homocysteine levels (Pfeiffer, 1999)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026