Major Depression
Conditions
Brief summary
Transcranial Direct Current Stimulation (tDCS) is a novel non-invasive brain stimulation treatment that is effective with no significant side effects. It can potentially be self-administered by patients in their own homes with remote monitoring, substantially reducing treatment costs and increasing accessibility, including to remote areas. This study will evaluate the feasibility and efficacy of home-administered tDCS treatment for depression.
Interventions
DEVICESoterix tDCS machine
Soterix tDCS machine - miniCT supervised neuromodulation system
Sponsors
The University of New South Wales
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Subject meets criteria for a DSM-IV Major Depressive Episode, lasting more than 4 weeks * Total MADRS score ≥ 20
Exclusion criteria
* Diagnosis of any DSM-IV psychotic disorder * History of drug or alcohol abuse or dependence in the preceding 3 months * High suicide risk * Clinically defined neurological disorder or insult * Metal in the cranium or skull defects * Skin lesions on the scalp (e.g. cuts, abrasions, rashes) at the proposed electrode sites * Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montgomery Asberg Depression Rating Scale for Depression (MADRS) | 6 months |
Countries
Australia
Outcome results
None listed