Parkinson Disease
Conditions
Keywords
Parkinson's disease, Action-effect prediction, Sensory attenuation, Voluntary action
Brief summary
The ideomotor theory of action control is considered to be central to the understanding of human voluntary action. According to the ideomotor theory, an action is represented in terms of its desired sensory effects and actions are selected by internally activating these effect representations. Recent imagery and behavioral studies showed that this anticipated representation of action-effects triggered a sensory attenuation, meaning a decrease of perceptive performances or a decrease of sensory event-related potentials (ERP) for an expected event. Thus, the sensory attenuation constitutes a relevant behavioral tool to investigate sensory anticipation impairment in patients with Parkinson's disease. In a behavioral paradigm, patients and matched control participants have to perform a perceptive task on predicted visual action-effects mixed with mispredicted visual action effects. Performances should be better in mispredicted visual action effects for control participants only.
Interventions
BEHAVIORALbehavioral observation
Sponsors
Fondation Ophtalmologique Adolphe de Rothschild
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Parkinson's disease * Normal or corrected vision
Exclusion criteria
* Other pathology or neurological or psychiatric history * Known pregnancy or breastfeeding * Absence of affiliation to the French Social Security * Person under legal protection * Patient's opposition to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| median score | baseline | scores measured with the Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) |
Countries
France
Outcome results
None listed