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Psychobiological Effects of Meditation on Offenders With Psychopathy

Psychological and Biological Effects of Intensive Mindfulness Meditation on Offenders With Dangerous and Severe Personality Disorder: A Randomised Controlled Trial

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02894203
Enrollment
60
Registered
2016-09-09
Start date
2016-09-30
Completion date
2017-02-28
Last updated
2016-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mindfulness, Yoga

Brief summary

The investigators aim to explore the psychobiological effects of a 5-day meditation intervention on offenders within dangerous and severe personality disorders (DSPD) unit at HMP Whitemoor. DSPD unit accommodates offenders with psychopathy or with two or more personality disorders. DPSD unit provides them with a 5-year rehabilitation programme that consists of group and individual therapy and aims to improve their self-regulation. This project includes a total of 60 participants and has two major methodological innovations. First, it will include yoga as an active control group that will be matched to the meditation intervention (which means it will have the same length and the same social components) and a passive control group that will be following their usual regimen. Thus, the effects of meditation will be contrasted with another type of intervention and with not receiving any intervention. The second methodological innovation is the combination of psychological and biological measures. Psychological measures include questionnaires (emotion regulation, mindfulness, stress) and cognitive measures (attention,empathy,behavioural control). Biological measures include EEG to measure brain activity related to empathy; gene expression and protein interlukin-6 to measure changes in immune system; and stress related hormone cortisol. The investigators also aim to determine to whom does meditation benefit the most by exploring how initial expectations of meditation, personality, mood and previous life adversity predict outcomes of meditation or yoga. The data will be collected at three time points: at baseline, immediately after and 10 weeks after the 5-day intervention. The investigators expect that meditation and yoga will similarly improve mental and physical health. If this hypothesis are confirmed, these results will extend previous findings on the benefits of meditation and yoga to vulnerable populations, and would provide a cost-effective addition to prisoner rehabilitation.

Interventions

BEHAVIORALMindfulness
BEHAVIORALYoga

Sponsors

Donders Centre for Cognitive Neuroimaging
CollaboratorOTHER
Coventry University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
MALE
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Male offenders with dangerous and severe personality disorder aged 18-65 who will remain in the prison until at least February 2017.

Exclusion criteria

* Major psychiatric or neurological disorders, previous meditation or yoga experience, unable to follow instructions in English,

Design outcomes

Primary

MeasureTime frameDescription
Change from baseline emotional regulationBefore the intervention, up to 2 weeks after the intervention and at 10-18 week follow-upDifficulties in Emotion Regulation Scale
Change from baseline attentionBefore the intervention, up to 2 weeks after the intervention and at 10-18 week follow-upAttention Network Task
Change from baseline self-awarenessBefore the intervention, up to 2 weeks after the intervention and at 10-18 week follow-upMindful Attention Awareness Scale
Change from baseline inflammatory gene expressionBefore the intervention and on the final day of the intervention

Secondary

MeasureTime frameDescription
Change from baseline social learningBefore the intervention, up to 2 weeks after the intervention and at 10-18 week follow-upSocial Learning Task (Diaconescu et al., 2014)
Change from baseline affective statesBefore the intervention, up to 2 weeks after the intervention and at 10-18 week follow-upProfile of Mood States
Change from baseline risk-takingBefore the intervention, up to 2 weeks after the intervention and at 10-18 week follow-upRisk-taking Task (Tymula et al., 2012)
Change from baseline empathyBefore the intervention, up to 2 weeks after the intervention and at 10-18 week follow-upSelf-assessment Manikin (Seara & Cardoso, 2012).
Change from baseline stressBefore the intervention, up to 2 weeks after the intervention and at 10-18 week follow-upPerceived Stress Scale

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026