Microbiota
Conditions
Brief summary
The aim of the study is to characterize and monitor the microbiome of premature infants born in the investigators facility until discharge from the NICU. The investigators will also examine the relationship between mode of delivery and the microbiome of the infant, while exploring various possible factors that may affect it. In addition, the investigators will compare the microbiome of premature infants to the microbiome of term babies born at the same time in the same facility.
Interventions
OTHERnon invasive sampling
Sponsors
Bar-Ilan University, Israel
Hadassah Medical Organization
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Premature infants ≤ 34 weeks of gestation admitted to the Neonatal Intensive Care Unit at Hadassah University Hospital, Mount Scopus and their mothers. The control group: * Neonates ≥ 37 weeks gestation of which 50 were delivered vaginally and 50 by Caesarean section at Hadassah University Hospital, Mount Scopus and their mothers.
Exclusion criteria
* Neonates with congenital anomalies or metabolic conditions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Definition the flora comprising the microbiome of premature and term babies | birth |
Secondary
| Measure | Time frame |
|---|---|
| Difference in the microbiome of the infants born vaginally and via caesarian section | birth |
| Change in the flora that constitutes the microbiome of premature babies | birth until adjusted age of 40 weeks gestation |
Countries
Israel
Outcome results
None listed