Effect of the Duration of Preoperative Fasting on Hypotension Induced by General Anesthesia in the Elderly Person

The Influence of Duration of Fluid Abstinence on Hypotension During General Anaesthesia Induction for Traumatic Hip Surgery in the Elderly

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02891122

Acronym

JEÛNE PREOP

Enrollment

Registered

2016-09-07

Start date

2014-10-31

Completion date

2015-07-31

Last updated

2016-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preoperative Fasting and Hypotension

Brief summary

This study aims to determine if prolonged fasting represents an independent risk factor for hypotension during induction of general anesthesia in the elderly.

Detailed description

Preoperative fasting aims to reduce the risk of adverse events (eg, inhalation), but may be responsible for dehydration whose consequence is a major hypotension. This problem of hypotension is important because it (MAP \<55 mmHg) is directly correlated to the occurrence of pejorative events on the cardiac and renal level and even more so that the duration of the hypotension is long.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

70 Years to No maximum

Healthy volunteers

Inclusion criteria

* Risk Score anesthetic ASA I-III * Patients ≥ 70 years * Suffering from a femoral neck fracture to be treated surgically: * either through prosthesis, * either by intramedullary nailing (gamma nail)

Exclusion criteria

* Risk Score anesthetic ASA IV * Patient on Angiotensin Converting Enzyme (ACE) inhibitors or ARBs (ARA2) within 10 hours before surgery * Obesity (BMI\> 35) or weight \<40kg * Need to make a rapid sequence induction * Inability to achieve the femoral block (standardization of induction) or patient refusal with respect to the technique.

Design outcomes

Primary

Measure	Time frame
Follow-up of the variation of the Mean arterial pressure	8 months

Countries

France

Outcome results