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Optimizing Medication Therapy for Patients Recently Discharged From Hospital

Optimizing Medication Therapy Outcomes for Complex Patients Transitioning From Acute to Primary Care

Status
Terminated
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02888782
Enrollment
89
Registered
2016-09-05
Start date
2016-12-08
Completion date
2018-06-29
Last updated
2018-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Disease

Brief summary

Patients who are discharged from hospital can be overwhelmed when they suddenly have to manage new conditions or medications. These changes can be particularly difficult for people on many medications or with multiple health conditions. There is a real risk that this will lead to emergency room visits, hospital readmission, and even death. In addition to endangering patients, these adverse events are very costly to the healthcare system. The good news is that these events can be preventable if patients receive care that is better coordinated. Patient-oriented research will be conducted to determine if a pharmacist-led medication therapy management service can improve health outcomes of 'medically complex' patients transitioning from acute to primary care in Newfoundland and Labrador (NL). This a more comprehensive service than their community pharmacist would normally provide. The program will use a new Pharmacist Clinic service to provide care and support which does not currently exist for patients in NL after they leave hospital. After discharge, patients will be randomly divided into two groups: one group will receive care as usual from their doctor; the other group will have their medications assessed by a clinic pharmacist within one week of hospital discharge along with their usual care from their doctor. The two groups will be compared to determine whether specialized pharmacist services after hospital discharge is satisfactory to patients/providers, improves patient health, and reduces emergency room visits, hospital readmissions, and repeat trips to the doctor. If successful, this project will help ensure that patients are taking the right medications in the right way, improving individual health and making better use of healthcare system resources.

Interventions

Sponsors

Memorial University of Newfoundland
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1. 50 years of age or older 2. Admitted to a General Medicine ward 3. Take 5 or more chronic medications

Exclusion criteria

1. Discharge to a long term care facility 2. Life expectancy less than 3 months 3. Have entered palliative care 4. Cognitive impairment (unless a responsible caregiver can provide consent and assist in participation) 5. Non-English speaking 6. Unable to provide informed consent

Design outcomes

Primary

MeasureTime frameDescription
Composite Hospital Utilization Rate30 days post dischargeA composite score of hospital readmission rate and ER visits

Secondary

MeasureTime frame
Number of Emergency Room Visits30 days post discharge
Rehospitalization Rate30 days post discharge
Mortality Rate30 days post discharge
Frequency of Family Physician Visits30 days post discharge

Other

MeasureTime frameDescription
Patient quality of life Short Form Health SurveyCollected at time of hospital dischargeMeasured using a Short Form Health Survey (SF-36)
Patient Satisfaction SurveyCollected 3 - 6 months after study enrollmentMeasured using a Likert scale questionnaire
Pharmacist Satisfaction SurveyCollected at the end of study period (12-15 months)Measured using a Likert scale questionnaire
Physician Satisfaction SurveyCollected at the end of study period (12-15 months)Measured using a Likert scale questionnaire

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026