Neural and Cognitive Mechanisms of Depression and Anxiety: a Multimodal MRI Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02888509

Enrollment

150

Registered

2016-09-05

Start date

2015-06-30

Completion date

2017-01-31

Last updated

2016-09-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Keywords

depression, anxiety disorder, bipolar disorder, Magnetic Resonance Imaging

Brief summary

To explore the neural and cognitive mechanisms of depression (including unipolar depression and Bipolar disorder) and anxiety using multimodal MRI techniques.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

16 Years to 55 Years

Healthy volunteers

Yes

Inclusion criteria

* Age range from 16 to 55 years old. * All patients were interviewed by two experienced psychiatrists using the Structured Clinical Interview for DSM-IV (patient edition)

Exclusion criteria

* Schizophrenia, mental retardation or personality disorder, any history of loss of consciousness, substance abuse, serious medical or neurological illness. * Subjects with contraindications to MRI

Design outcomes

Primary

Measure	Time frame	Description
Brain structural and functional changes in patients	one time point	Structure and function changes in patients will be assessed by Voxel-based morphometry analysis for structural changes, as well as Regional homogeneity, Amplitude of lowfrequency fluctuation, etc, for functional changes.

Countries

China

Contacts

Primary ContactHuafu Chen

chenhf@uestc.edu.cn

Outcome results