Obsessive Compulsive Disorder (OCD)
Conditions
Brief summary
Obsessive Compulsive Disorder (OCD) often becomes chronic if not treated. Exposure and response prevention (ERP) is recommended psychological treatment. The OCD-team at Haukeland University hospital has developed a concentrated 4-day treatment format which has been evaluated as part of standard care. Next step in the methodological development is to conduct a randomized controlled trial where the 4-day format is compared to self-help and waiting list. The study will be conducted at Solvang DPS, Sørlandet Hospital. Participants (16 in each group) are ordinary patients (\>18 yrs) entitled to care in the specialist health care.
Interventions
BEHAVIORALConcentrated exposure treatment (cET)
Psychological cognitive behavioral treatment
BEHAVIORALSelf-help
Sponsors
Sorlandet Hospital HF
Haukeland University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
OCD-patients referred to the OCD-team at Sørlandet Sykehus, Solvang DPS will be included. Inclusion criteria * Outpatients * ≥ 18 years of age * Fulfilling diagnostic criteria of OCD according to the DSM-5 * Y-BOCS ≥ 16 * Fluent in Norwegian * Signed informed consent
Exclusion criteria
* OCD symptoms primarily associated with hoarding * Ongoing substance abuse/dependence * Bipolar disorder or psychosis * Ongoing suicidal ideation * Mental Retardation, based on previous medical history * If using antidepressants: * Not on stable dosage 4 weeks before the intervention * Unwilling to remain on stable dosage during the four intervention days * Unwilling to refrain from anxiety reducing substances, such as anxiolytics (e.g. benzodiazepines) and alcohol during the two days of exposure. * Patients living \> 1.5 hour drive by car/ train from the treatment location. * Patients with a BMI-index considered too low for participation in psychological treatment * Patients with a full course of prior CBT for OCD.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in Y-BOCS from pre cET-treatment to post treatment/ waiting list/ self-help | Pre-treatment, 1 week post, minimum nine weeks after pre-treatment, minimum six months follow up | Y-BOCS changes will for all conditions be calculated by two approaches which will be compared. |
| Changes i OCD diagnostic status (DSM-5) as measured by SCID | Pre-treatment, 1 week post, minimum nine weeks after pre-treatment, minimum six months follow up | — |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Generalized anxiety | Pre-treatment, 1 week post, minimum nine weeks after pre-treatment, minimum six months follow up | Generalized Anxiety Disorder Assessment 7 (GAD-7) is a brief 7-item self-report measure for generalized anxiety symptoms. Although developed for measuring severity of generalized anxiety disorder, the GAD-7 measures severity of general anxiety symptoms common to several anxiety disorders |
| Depression | Pre-treatment, 1 week post, minimum nine weeks after pre-treatment, minimum six months follow up | Patient Health Questionnaire, (PHQ-9) is a 9-item self-report questionnaire measuring level of depressive symptoms. Items are scored on a scale from 0 (not at all) to 3 (nearly every day). |
| Well-being | Pre-treatment, 1 week post, minimum nine weeks after pre-treatment, minimum six months follow up | The Warwick-Edinburgh Mental Well-being Scale (WEMWBS) will be administered to assess mental well-being. This scale has 14 items covering different aspects of mental health related to mental well-being. |
| Client satisfaction | 1 week post Concentrated Exposure Treatment | Client Satisfaction Questionnaire (CSQ-8) is an eight-item self-report form where patients report their level of satisfaction with the treatment they have undergone. |
| Insomnia | Pre-treatment, 1 week post, minimum nine weeks after pre-treatment, six months follow up | The Bergen Insomnia Scale (BIS) will be used to screen for sleep disturbances. The scale has six items covering different aspects of sleep disturbances the past 4 weeks |
| Work and social adjustment | Pre-treatment, 1 week post, minimum nine weeks after pre-treatment, minimum six months follow up | The Work and Social Adjustment Scale (W & SAS) is a short questionnaire measuring work and social adjustment. |
Outcome results
None listed