Hyperglycemia
Conditions
Brief summary
Recently, there are some new classes of anti-diabetic drugs availible in Taiwan. In this study, we will observe the change in inflammation and energy homeostasis in type 2 diabetic outpatient, who receiving a new anti-diabetic drugs.
Detailed description
Recently, there are some new classes of anti-diabetic drugs availible in Taiwan. However, the effects of these anti-diabetic drugs should be further evaluated. Specially, the effects on inflammation and energy homeostasis are still not well assessed. In this study, we will observe the change in inflammation and energy homeostasis in type 2 diabetic outpatient, who receiving a new anti-diabetic drugs.
Interventions
DRUGanti-diabetic drug
Add-on anti-diabetic drug in type 2 diabetic patients
Sponsors
Taichung Veterans General Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Type 2 diabetic outpatient
Exclusion criteria
* Refusal of anti-diabetic drugs * Preganacy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HbA1c | 3 months |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Body-composition | 3 months | energy homeostasis |
| Fasting glucose | 3 months | — |
| Hypoglycemia | 3 months | — |
| Brain-Derived Neurotrophic Factor (BDNF) | 3 months | energy homeostasis |
| Ankle-Brachial Index (ABI) | 12 months | peripheral artery disease |
| Orexin-A | 3 months | — |
| Vascular Cell Adhesion Molecule 1 (VCAM-1) | 3 months | inflammation |
Countries
Taiwan
Contacts
Primary ContactI-Te Lee, MD,PhD
Outcome results
None listed