Detection no Invasive of a Silent Myocardial Ischemia

Silent Myocardial Ischemia in Patients With Diabetes Type 2: Diagnostic Value of Myocardial Strains Left Ventricular Resting Echocardiography 2D and 3D, Compared to Stress Echocardiography

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02885428

Enrollment

Registered

2016-08-31

Start date

2015-04-15

Completion date

2018-04-17

Last updated

2022-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Silent Myocardial Ischemia, Type 2 Diabetes

Brief summary

The pathophysiological features of myocardial diabetic subject combined with cardiac autonomic neuropathy were behind the quietness of myocardial ischemia, known as silent myocardial ischemia (IMS). These patients have the risk to remain asymptomatic until the sudden onset of a myocardial infarction, or even sudden death. That is why the investigators want to evaluate the contribution of non-invasive tools to stand in the diagnosis of IMS patients with diabetes type 2, asymptomatic heart on map: Technical myocardial speckle tracking in studying strains overall average left ventricular (longitudinal, circumferential and radial) measured in 2D and 3D at rest, compared to stress echocardiography with dobutamine (ESD)

Interventions

DEVICEechography

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* With at least two cardiovascular risk factors including: hypertension, dyslipidemia, smoking active or interrupted for less than 3 years, family history (relatives of the 1st degree) Accident major CV before 60. * Or whatever the level of risk factors: peripheral artery disease and / or carotid atherosclerosis, or proteinuria

Exclusion criteria

* Valvular heart disease (severe to moderate valvular ) , hypertrophic , dilated , chronic lung * History of cardiotoxic chemotherapy * Atrioventricular blocks of degree * Asthma * Recent stroke within a month * Bilateral carotid stenosis tight * Glaucoma untreated narrow angle * Subject to exclusion period (determined by a previous study or in progress) * Inability to give informed about information * patient under judicial protection * patient guardianship or curatorship * Current pregnancy (women of childbearing age ) * Breastfeeding

Design outcomes

Primary

Measure	Time frame
diagnostic of the silent myocardial ischemia	80 minutes

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026