Effect of Nasal Highflow on Right Heart Function

Hemodynamic Effects of Nasal Highflow on Patients With Chronic Respiratory Insufficiency and Pulmonary Hypertension

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02885116

Acronym

HÄMOFLOW

Enrollment

Registered

2016-08-31

Start date

2016-01-31

Completion date

2018-02-28

Last updated

2018-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Hypertension

Keywords

NHF, pulmonary hypertension

Brief summary

In this study effect of NHF on pulmonary thermodynamic parameters will studied.

Interventions

DEVICENasal high flow (NHF) supplementation

use of NHF for 20 min/ 35 l/min, at the end of this period right heart catheterization

DEVICEoxygen supplementation

hypoxemic patients will use their normal oxygen supplementation durch right heart catheterization

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* stable disease * hypoxemic respiratory disorder

Exclusion criteria

* decompensation * acute illness

Design outcomes

Primary

Measure	Time frame	Description
changes in mean pulmonary pressure (PAPm)	20 min	measured in mmHg

Secondary

Measure	Time frame	Description
changes in wedge pressure (PC)	20 min	mmHg
changes in cardiac index (CI)	20 min	l/min/qm

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026