Pain
Conditions
Brief summary
The purpose of this study is to evaluate the tolerance and the efficiency of subcutaneous administration of Paracetamol for patients in palliative care.
Detailed description
Subcutaneous administration is the most commonly used way for palliative care and geriatric service. A lot of drugs are recommended with subcutaneous administration, but their use is performed out of the Marketing Authorization, and fewer data exist about this practice in literature. Paracetamol is a grade 1 analgesic not currently recommended for subcutaneous injection, because of the lack of validated references. However this kind of administration is usually performed for Paracetamol in the French palliative care services related with its advantages for patients, as analgesic or antipyretic. The assumption of the study is that the use of paracetamol subcutaneously is possible with a good tolerance for hospitalized patients in palliative care service.
Interventions
None listed
Sponsors
Centre Hospitalier Régional Metz-Thionville
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* older than 18 years old * indication of paracetamol by subcutaneous injection, as an analgesic or an antipyretic
Exclusion criteria
* opposition to gather data patient * subcutaneous administration of paracetamol during the last week before the inclusion of the patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of the severe or not adverse effects on the injection site | 8 days |
Secondary
| Measure | Time frame |
|---|---|
| as antipyretic, a feedback of tympanic temperature below 38°C during the two hours after injection | 8 days |
| as analgesic, the decrease of pain (decrease of 30 in the numerical scale score, or a Algo+ scale score lower than 2/5) | 8 days |
Countries
France
Outcome results
None listed