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Validation Study of the Accuracy of E/e' in Estimating Left Ventricular Filling Pressure

Validation Study of the Accuracy of E/e' in Estimating Left Ventricular Filling Pressure

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02883504
Acronym
EUROFILLING
Enrollment
85
Registered
2016-08-30
Start date
2014-11-01
Completion date
2016-08-01
Last updated
2026-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Doppler Echocardiography

Keywords

E/e' ratio, Doppler echocardiography, filling pressure, Left Ventricular end-Diastolic Pressure

Brief summary

The non-invasive estimation of left ventricular end diastolic pressure (LVeDP) is a main goal for performing an echocardiography in the routine clinical practice. Conflicting evidence exists about mitral E/e' ratio reliability for predicting high LVeDP

Interventions

PROCEDUREEcho-Doppler examination and left heart catheterization

Sponsors

Rennes University Hospital
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age over 18 years * Patient performing an echocardiography in the routine clinical practice * Informed consent given

Exclusion criteria

* Severe valve disease, valvular prostheses, calcification of the mitral valve, the history of myocardial infarction, atrial fibrillation, severe arrhythmias not allowing the Doppler analysis, pacemaker and any image by inadequate Doppler ultrasound * Major person under legal protection (backup justice, trusteeship, guardianship), person deprived of liberty.

Design outcomes

Primary

MeasureTime frameDescription
Invasive evaluation of left ventricular end diastolic pressureD0Left heart catheterization

Secondary

MeasureTime frameDescription
Non-invasive evaluation of left ventricular end diastolic pressureD0Echo-Doppler

Countries

France

Contacts

STUDY_DIRECTORErwan Donal, Md, PhD

Rennes University Hospital

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 13, 2026