Peritonitis
Conditions
Keywords
peritonitis, solutions, normal saline, infection, peritoneal lavage
Brief summary
Super Oxidized Solution (SOS) was used in peritonitis and results were compared by using normal saline solution in two groups. Abdominal fluid was taken to check for bacterial load after giving lavage with SOS solution and in other group normal saline. SOS is a high level disinfectant, non-flammable and no special training is required to handle it.
Detailed description
Aim - To investigate the efficacy of super-oxidized solution (SOS) over normal saline in peritonitis. The investigators objectives are to present the potential clinical impact of intraperitoneal lavage with solutions for early recovery of the patient by reducing the infection rate. Methods - A double-blind random clinical trial was performed in 240 patients diagnosed as peritonitis at MMIMSR, Mullana, Ambala, India, from December 2014 - November 2015. Subjects were divided into 2 groups, i.e. 120 patients in the study group and 120 cases in the control group. Both the groups underwent peritoneal lavage ; the study group received SOS where as control group underwent normal saline lavage. The effectiveness of both the solutions were compared.
Interventions
PROCEDURESuper Oxidized Solution in group I
Two groups were made as group I and group II. Peritoneal Lavage was given with SOS and normal saline in group I. in group II only normal saline wash was given.
Sponsors
Maharishi Markendeswar University (Deemed to be University)
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
1 Days to 90 Years
Healthy volunteers
No
Inclusion criteria
* gastric, duodenal, ileal perforation, appendicitis * those patients were willing to participate and the informed consent was taken
Exclusion criteria
* evidence of enteric encephalopathy * liver diseases * renal diseases * heart disease * known allergy to any substance * multiple trauma or organ injury * any gynaecological etiology
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the investigators measured the infection rate by checking the bacterial load during after surgery | average of one year | The investigators asked about the infection, early recovery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The Results Were Measured In the Form of the, Early Recovery, Early Bowel Sounds | With in 10 -20 days | the condition of the patient measured in the form of early bowel sounds, fever and discharge from the operated area |
Outcome results
None listed