Chronic Kidney Disease
Conditions
Keywords
CAPD, Peritoneal solute transport rate, Dialysis adequacy
Brief summary
The aim of study was to evaluated the correlation between plasma levels, dialysate appearance rate of VEGF, inflammatory cytokines (IL- 6, procalcitonin) and PSTR, dialysis adequacy in CAPD patients.
Detailed description
This cross -sectional study measured IL-6, procalcitonin and VEGF level in plasma and overnight effluent. PSTR of small solutes was evaluated by standard peritoneal equilibration test (standard PET). Weekly Kt/V and creatinine clearance (CCr ) were evaluated in all patients.
Interventions
OTHERMeasure plasma and dialysate level of IL-6, procalcitonin and VEGF
correlation between plasma levels, dialysate appearance rate of VEGF, inflammatory cytokines (IL- 6, procalcitonin) and PSTR, dialysis adequacy in CAPD patients.
Sponsors
Bangkok Metropolitan Administration Medical College and Vajira Hospital
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Stable CAPD patients without previous history of peritonitis
Exclusion criteria
* HIV * Other infections, tuberculosis or on immunosuppressive drugs, * Autoimmune disease, * Cancer * Diagnosis of permanent ultrafiltration failure .
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| plasma level of VEGF, IL-6 and procalcitonin with the PSTR and dialysis adequacy in CAPD patients | 2 years | measure in pg/ml |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cytokines in diabetic and non-diabetic group | 2 years | All cytokines in plasma and blood |
Countries
Thailand
Outcome results
None listed