Blood Pressure Medication, Comorbidities, Complications (Subarachnoid Hemorrhage), Intracranial Aneurysm Size, Sleep Apnea (Defined as Apnea Hypopnea Index > 5/h)
Conditions
Keywords
Sleep Apnea, Aneurysm, Subarachnoid Hemorrhage, Blood Pressure.
Brief summary
Patients with intracerebral aneurysm will be screened for sleep apnea using out of center polysomnography/polygraphy. Baseline blood pressure and medication will be assessed. Patients will be followed for up to 5 years to examine the increase in aneurysm size, rupture rate and changes in medication.
Detailed description
Patient presenting to the outpatient center for neurological of neurosurgical management of intracerebral aneurysm will be recruited. Sleep apnea will be assessed by questionnaire and out of center polygraph/polysomnography. Medication, comorbidities and blood pressure will be recorded. Change in aneurysm size and blood pressure medication will be evaluated annually for up to 5 years. Frequency of subarachnoid hemorrhage and increase in aneurysm size will be assessed.
Interventions
DEVICECardiorepiratory Polygraphy
Sleep apnea screening by out-of-center polysomnography/polygraphy
Sponsors
University Hospital, Bonn
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Intracerebral aneurysm * Age \>= 18yrs. * Ability to give informed consent
Exclusion criteria
* Stroke within 3 month of study inclusion.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood pressure medication | Baseline | Blood pressure medication at baseline will be accessed. |
| Blood pressure | Baseline | Blood pressure on baseline visit will be accessed. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Subarachnoid hemorrhage | 5 years | Rate of aneurysm rupture and subarachnoid hemorrhage will be accessed annually. |
| Increase in size of aneurysm | 5 years | — |
| Change in blood pressure medication | 5 years | Blood pressure medication will be accessed on annual follow-up for up to 5 years. |
Countries
Germany
Contacts
Primary ContactSebastian Zaremba, MD
Backup ContactErdem Guersir, MD, PhD
Outcome results
None listed