Infant, Newborn, Disease
Conditions
Brief summary
This study aims to assess whether the electrical signal of the diaphragm (diaphragm electromyogram) and the ratio of that to tidal volume (amount of air breathed in and out of the lungs) can predict which infants will be successfully extubated (have the breathing tube removed without needing it replaced.)
Detailed description
This study aims to assess whether the electrical signal of the diaphragm (diaphragm electromyogram) and the ratio of that to tidal volume (amount of air breathed in and out of the lungs) can predict which infants will be successfully extubated (have the breathing tube removed without needing it replaced.)
Interventions
DEVICERecording of diaphragm EMG
Recording of diaphragm EMG prior to extubation using surface diaphragm electromyography
Sponsors
King's College Hospital NHS Trust
King's College London
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
0 Days to 12 Months
Healthy volunteers
No
Inclusion criteria
* intubated and mechanically ventilated on NICU
Exclusion criteria
* major congenital abnormalities
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Magnitude of diaphragm EMG | One hour | Magnitude of diaphragm EMG |
| Ratio of diaphragm EMG to tidal volume | One hour | Ratio of diaphragm EMG to tidal volume |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Extubation success | 48 hours | Extubation success is define as remaining free of invasive mechanical ventilation. Whether the above measures of diaphragm EMG can predict such success will be investigated |
Countries
United Kingdom
Outcome results
None listed