Fibrosis
Conditions
Brief summary
The investigators conducted a randomized controlled trial to describe if multidisciplinary and patient-centered transitional care interventions for patients with cirrhosis post-TIPS can improve compliance behavior and reduce complications post-TIPS after discharge.
Interventions
BEHAVIORALthe prevention of complications post-TIPS
Continuous nursing through telephone follow-up, family visits, and WeChat guided patients to prevent gastrointestinal bleeding, infection and constipation ,intake quality low-protein diet, recognize minimal encephalopathy, monitor blood ammonia, return visit regularly, deal with adverse drug reactions of anticoagulant.
Sponsors
Shihezi University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Clinical diagnosis of diagnosis of cirrhosis; * Child-Pugh Score \<10; * Informed Consent.
Exclusion criteria
* Age \<18 years; * Right ventricular failure; * Severe systemic infection; * Hepatocellular carcinoma (HCC); * Terminal disease; and * Failure to provide written consent to participate in the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The compliance behavior associated with complications post-TIPS | 1 and 3 months after discharge | It was surveyed using a self-designed questionnaire based on evidence. The questionnaire includes 6 items that address taking medicine on time, quality low-protein diet intake, going to sleep at a regular time, moderate exercise, emotion regulation, regular follow-up. Item responses are on a 4-point scale (0 = never to 3 = always). Data were collected by face-to-face interviews with trained transition nurses. Change is being assessed |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| incidence of adverse events (shunt dysfunction and hepatic encephalopathy) | 1 and 3 months after discharge | Change is being assessed |
| Child-Pugh scores | Baseline, 1 and 3 months after discharge | Change is being assessed |
| Blood ammonia levels | Baseline, 1 and 3 months after discharge | Change is being assessed |
Outcome results
None listed