Value of Radionuclide Cisternography

VALUE OF RADIONUCLIDE CISTERNOGRAPHY IN PATIENTS WITH CEREBROSPINAL FLUID LEAK

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02876614

Acronym

VERTICAL

Enrollment

113

Registered

2016-08-24

Start date

2005-01-31

Completion date

2005-12-31

Last updated

2016-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CSF Leak, Fistula

Keywords

radionuclide cisternography, CSF leak, imaging

Brief summary

Radionuclide cisternography (RC) is a nuclear medicine examination based on intrathecal injection of \[111In\]diethylenetriaminepentaacetic acid (\[111In\]DTPA). It is prescribed for two recommendations: detection of cerebrospinal fluid (CSF) leak/fistula and diagnosis of normal pressure hydrocephalus. In the search part of CSF leak/fistula, RC offers the benefit of a 24-hour study of CSF unlike other reference tests. In addition to SPECT/CT imaging, the radiopharmacist performs sampling in nasal cavities and throat of the patient to collect a possible flow of CSF. These samples are analysed by radioactivity measurements and bring an added value to the exam. The interest of this examination for management of CSF leak/fistula remains unclear. The aim of this study is to identify and analyse results of all RC examinations performed since 2005 in the Nuclear Medicine department of the Neurological Hospital. The full analysis of patients will allow discussing the role of RC in management of CSF leak/fistulae in clinical practice.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* patients who received a convocation for realization of RC (extraction with GERA, software of Nuclear Medicine)

Exclusion criteria

* patients who received a convocation for realization of RC with valve protocol

Design outcomes

Primary

Measure	Time frame	Description
RC /SPECT/CT imaging	one week	Results of RC including results of SPECT/CT imaging and results of swabs counting (nasal cavities and throat or ear if applicable)

Outcome results