Food Design for Improved Day-long Glycaemic Regulation

The Effect on Glucose Tolerance at a Second Meal Provided After Breakfast Meal Giving Late Increment in Postprandial Glycaemia

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02876029

Enrollment

Registered

2016-08-23

Start date

2014-09-30

Completion date

2015-03-31

Last updated

2016-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Poor Glycemic Control

Brief summary

The study focus is on the possible improvement in glucose tolerance at a second standardized meal that can be achieved when preceded by a test meal with a low GI and a high GP.

Detailed description

A study in healthy subjects using spaghetti as the test breakfast and a white wheat bread as the reference. Glycaemia, insulinaemia, NEFA, TG and subjective appetite are studied up to the time of the lunch meal that is served 4h after breakfast. After lunch the blood sampling continues for 2 hours.

Interventions

OTHERReference

the reference product used

OTHERTest product

The test Product used

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* BMI 19-25

Exclusion criteria

* Smoker, Diabetes, Gluten intolerance, vegetarian

Design outcomes

Primary

Measure	Time frame
Glucose	0-6 h

Secondary

Measure	Time frame
Non-esterified fatty acids (NEFA)	0-6 h
Triglycerides (TG)	0-6 h
Appetite rating (Visual Analogue Scale)	0-6 h
Insulin	0-6 h

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026