Cerebrospinal Fluid IL-6, IL-8 and PCT as Early Marker of an Intrathecal Infection in Neurosurgical Patients

Early Detection of CSF Infection in Neurosurgical Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02875808

Enrollment

Registered

2016-08-23

Start date

2014-08-01

Completion date

2017-12-12

Last updated

2018-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

External Ventricular Drainage Associated Infection, Intrathecal Infection

Brief summary

The value of CSF IL-6, IL-8 and Procalcitonin in detecting an early diagnosis of intrathecal infection in neurosurgical patients with an external ventricular drainage is evaluated.

Detailed description

The value of CSF IL-6, IL-8 and Procalcitonin in detecting an early diagnosis of intrathecal infection in neurosurgical patients with an external ventricular drainage is evaluated.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* external ventricular drainage * informed consent

Exclusion criteria

* no informed consent * prior intrathecal infection * prior systemic infection / sepsis

Design outcomes

Primary

Measure	Time frame
increasing IL-6, IL-8 and PCT prior to an clinically apparent intrathecal infection/ a detection with the goldstandard	08/ 2014 - 12/ 2016

Countries

Germany

Outcome results