Urticaria
Conditions
Brief summary
Chronic spontaneous urticaria is an inflammatory disease which is characterized with intermittent or daily urticaria. This diseases lasts for more than 6 weeks. Several recent studies have suggested a role for vitamin D in modulation of immune system and pathogenesis of chronic urticaria.
Interventions
DRUGVitamin D3 (High dose)
Daily 4000 unites vitamin D
DRUGVitamin D3 (Low dose)
Daily 600 unites vitamin D
Sponsors
Shiraz University of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Uriticaria or angioedema daily or more than 3 days a weeks for at least 6 weeks
Exclusion criteria
* Physical urticaria aquired or hereditary angioedema Calcium level \> 10.3 mg/dl Glomerular filtration rate \<50 Sarcoidosis Primary hyperparathyroidism Granulomatous diseases Malignancies Pregnancy Lactation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Urticaria symptom severity questionnaire after 1 week | 1 weeks | Urticaria Symptom Severity ranging from 0 to 93 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Urticaria symptom severity questionnaire after 6 week | 6 weeks | Urticaria Symptom Severity ranging from 0 to 93 |
| Urticaria symptom severity questionnaire after 12 week | 12 weeks | Urticaria Symptom Severity ranging from 0 to 93 |
Countries
Iran
Contacts
Primary ContactKeramatallah Jahanshahi, MD
Outcome results
None listed