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5 Year Follow-up of Adolescents With Knee Pain

5 Year Follow-up of Adolescents With Knee Pain - a Prospective Cohort Study of 504 Adolescents

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02873143
Enrollment
540
Registered
2016-08-19
Start date
2016-09-30
Completion date
2017-01-31
Last updated
2017-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Pain, Patellofemoral Pain Syndrome

Brief summary

The prevalence of adolescent knee pain is 33%, and patellofemoral pain (PFP) is the most common diagnosis with a nontraumatic onset. The 5-year prognosis of adolescent PFP compared with other types of knee pain is unknown. In 2011, a cohort of 2200 adolescents aged 15 to 19 years answered an online questionnaire on musculoskeletal pain. Of these, 504 reported knee pain, and 153 of these were clinically diagnosed with PFP. Now, after 5 years, the 504 adolescents, as well as 252 randomly selected adolescents who did not report knee pain in 2011, will be contacted again to gain insights into their prognosis.

Interventions

OTHERNo intervention

No intervention

Sponsors

Research Unit for General Practice in Aalborg
CollaboratorOTHER
University of Southern Denmark
CollaboratorOTHER
Copenhagen University Hospital, Denmark
CollaboratorOTHER
Aalborg University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
15 Years to 19 Years
Healthy volunteers
Yes

Inclusion criteria

From the 504, 153 were diagnosed with PFP, the criteria for which included: \- insidious onset of anterior knee or retropatellar pain for longer than 6 weeks that was provoked by at least 2 of the following: prolonged sitting or kneeling, squatting, running, hopping, or stair climbing; tenderness on palpation of the patella; pain when stepping down; or double-leg squatting.

Exclusion criteria

were: * concomitant injury or pain from the hip, lumbar spine, or other knee structures * self-reported patellofemoral instability * knee joint effusion.

Design outcomes

Primary

MeasureTime frameDescription
Knee pain during the last week5 yearsAll subjects are asked if they experienced knee pain during the last week

Secondary

MeasureTime frameDescription
Frequency of knee pain5 yearsFrequency of knee pain divided into (almost daily, several times per week, weekly, monthly, rarely, never
When did your knee pain resolve5 years
Pain in other regions of the body5 years
Seeking medical attention for your knee pain5 years
Previous treatments for your knee pain5 year
Use of pain medication5 years
Worst pain last week5 yearsMeasured on a numeric rating scale
Knee pain during the last 30 days5 yearsDid you experience knee pain during the last 30 days?
Health-related quality of life5 yearsMeasure with the EQ-5D-3L
The influence of knee pain on choice of activity level, mood, choice of education and professional career5 years
Physical activity level5 yearsMeasured with the IPAQ
Number of sports participation per week5 years
The effect of knee pain on sports participation5 years
Self-reported sleep problems5 yearsAssessed by asking three questions related to: trouble falling asleep, wake several times per night and trouble staying asleep.
Knee Injury and Osteoarthritis Outcome score5 years

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 21, 2026