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Developmental Language Difficulties: Behavioural and Electrophysiological Studies

Developmental Language Difficulties: Behavioural and Electrophysiological Studies of the Connections Between Spoken and Written Language and Specificity of These Disorders

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02872870
Acronym
LANGAGE
Enrollment
196
Registered
2016-08-19
Start date
2012-03-31
Completion date
2016-06-30
Last updated
2016-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dyslexia, Dysphasia

Keywords

language disorders, developmental disorders of oral and written language

Brief summary

This study will help to better characterize oral and written language disorders and determine if these disorders are continuous or not. The participants ( dyslexic and dysphasic patients and control adults) will carry out an auditory lexical decision task during which an electroencephalogram (EEG) will be recorded.

Interventions

BEHAVIORALauditory lexical decision task
DEVICEelectroencephalogram

Sponsors

Université de Lille 3
CollaboratorUNKNOWN
Université Catholique de Louvain
CollaboratorOTHER
Lille Catholic University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
8 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

(patients): * Non-verbal intelligence quotient (IQ) less than 85 according to the Wechsler Intelligence Scale for Children (WISC) perceptual index * Specific oral language disorders diagnosed by the multidisciplinary team (neurologist, psychologist, speech therapist): understanding language deficit, estimated by the test SCOTLAND (Lecocq, 1996) and / or vocabulary test (Dunn Thiébaud). * Specific written language disorders (dyslexia) diagnosed by a multidisciplinary team according to a test that can objectify the late reading (Alouette) and locate deficits (EVALEC) * Be affiliated to a social security regimen * Have signed an informed consent or signed by the parents if the patient is minor * Aged at least 8 years old Inclusion Criteria (controls) * Non-deficit (\>85) non-verbal Wechsler Scale (codes and matrices) * No specific oral language disorders * No specific written language disorders (dyslexia) * Be affiliated to a social security regimen * Have signed an informed consent or signed by the parents if the patient is minor * Aged at least 8 years old

Exclusion criteria

* Mother tongue other than French * Non-verbal reasoning abilities below 85 measured by the WISC 4 (for patients only) and Non-verbal capacities of reasoning lower than the normal measured by the non-verbal scale of Wechsler (for controls only) * Presence of pervasive developmental disorders * No affiliation to a social security regimen * Absence of signature of the informed consent * Subject of less than 8 years

Design outcomes

Primary

MeasureTime frameDescription
Score EVALEC reading testat inclusionFor test performance, clinical groups will be compared with its controls.
Score of reading comprehension testat inclusionFor test performance, clinical groups will be compared with its controls.
Score of Khomsiat inclusionThe objective of this group of different tests is to evaluate comprehension and production of oral language. For test performance, clinical groups will be compared with its controls.
Score Alouette reading testat inclusionIn this test, the participant has to read in a loud voice a text, during three minutes. The final score takes into account the speed and the number of errors. For test performance, clinical groups will be compared with its controls.
Score silence reading testat inclusionA group of letters will be presented and the participant has to say if this letters compose a known word. For test performance, clinical groups will be compared with its controls.

Secondary

MeasureTime frameDescription
Correlation between electroencephalography power spectra and clinical outcomeat inclusionFor test performance, clinical groups will be compared with its controls.
Measure of the electroencephalography power spectraat inclusionFor test performance, clinical groups will be compared with its controls.

Countries

Belgium, France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026