Acute Respiratory Distress Syndrome
Conditions
Brief summary
Evaluation of pulmonary edema is a key factor in monitoring and guidance of therapy in acute respiratory distress syndrome (ARDS) patients. To date, methods available at the bedside for estimating the physiologic correlate of pulmonary edema, extravascular lung water(EVLW), often are unreliable or require invasive measurements. The purpose of the this study is to develop a novel approach to reliably assess extravascular lung water by electrical impedance tomography(EIT).
Interventions
None listed
Sponsors
Sichuan Provincial People's Hospital
Study design
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
Patients will be included in this study if the following criteria have been met: 1. Males and females \> 18 years old and \<85 years old (non-pregnant, non-lactating females). 2. Patients fulfilled the Berlin diagnostic criteria of ARDS 3. Signed written informed consent has been obtained 4. Patients had monitoring system Pulse-Induced Contour Cardiac Output (PiCCO)
Exclusion criteria
1. Females who are pregnant or lactating. 2. Patients with contraindication of EIT(Skin abrasions or wounds in the chest area.Patients with pacemakers or paced EKG rhythms.Thoracic deformity. Severe subcutaneous emphysema) 3. Patients \<18 years old or \> 85 years old 4. Patients Without monitoring system Pulse-Induced Contour Cardiac Output (PiCCO) 5. Patients with Cardiac function of grade 4 or patients with acute myocardial infarction or acute coronary syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison between a novel EIT-based method to estimate pulmonary edema (lung water ratio-EIT ) with a conventional measurement for EVLW using trans-cardiopulmonary thermodilution technique | once the patient was consented and enrolled |
Countries
China
Contacts
Primary ContactHongli He, Ph.D
Outcome results
None listed